AI Article Synopsis
- The study analyzed the survival rates and outcomes of 23 maxillary sinus cancer patients who underwent surgery and post-operative radiotherapy over a 10-year period at Vigo University Hospital.
- The 3-year overall survival rate was found to be 47.8%, with a local tumor control rate of 60.8%.
- Key factors impacting survival and local control included clinical stage, tumor location, and the presence of positive resection margins, with local recurrence identified as the primary cause of treatment failure.
Article Abstract
Objective: To describe the survival and outcome of maxillary sinus cancer in patients managed with surgery and post-operative radiotherapy during the last 10 years in our hospital.
Patients And Method: Descriptive, retrospective, non-randomized study of 23 patients with cancer of the maxillary sinus managed at the Vigo University Hospital Complex, Spain, with radical surgery and post-operative radiotherapy, between 1995 and 2004.
Results: The 3-year actuarial survival was 47.8% and the adjusted actuarial survival was 60.8%. Permanent local tumour control was achieved in 60.8% of cases (14/23). Local tumour recurrence was the main cause of treatment failure (33.3%; 4/12). The most significant prognostic factors affecting local tumour control and survival were: clinical stage (P< .031), suprastructural location of the tumour (P< .001), and presence of positive resection margins (P< .001).
Conclusions: Local recurrence was found to be very high and generally the main cause of death. New treatment protocols should be assessed.
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