We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878241 | PMC |
http://dx.doi.org/10.3201/eid1307.070068 | DOI Listing |
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