Introduction: Ecthyma gangrenosum is known as a characteristic lesion of Pseudomonas aeruginosa sepsis and is usually seen in immunocompromised patients.
Case Presentation: A previously healthy 63-year-old man was admitted with sloughy necrotic ulcerations of the skin over his sternum. He was afebrile and in good condition. A skin biopsy revealed ecthyma gangrenosum. Blood cultures remained sterile, but a culture of biopsy material grew Pseudomonas aeruginosa.
Conclusion: Ecthyma gangrenosum may develop even in the absence of bacteremia and even in immunocompetent patients. It should be considered as a possible diagnosis even when a previously healthy patient has negative blood cultures.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259368 | PMC |
http://dx.doi.org/10.1186/1752-1947-2-14 | DOI Listing |
Rev Med Chil
July 2024
Resident Department of Dermatology, Faculty of Medicine, University of Chile, Santiago, Chile.
This report describes the case of a 64-year-old female patient, with multiple comorbidities which presented an ecthyma gangrenosum due to Klebsiella pneumoniae confirmed by blood and tissue cultures. It finally ended in the amputation of the limb. The case is presented given the low prevalence of positive cultures for this microorganism in this pathology associated to devastating consequences for the patient.
View Article and Find Full Text PDFMayo Clin Proc
January 2025
Department of Dermatology, Mayo Clinic, Rochester, MN.
Dermatol Pract Concept
October 2024
Department of Geriatric - wound and healing, Rothschild Hospital, Sorbonne University, Paris, France.
J Ayub Med Coll Abbottabad
November 2024
Ziauddin Hospital KDLB, Karachi-Pakistan.
Ecthyma gangrenosum is a rare and severe skin disease that is typically accompanied by a systemic infection caused by Pseudomonas aeruginosa bacteria. It manifests as painful, necrotic lesions surrounded by redness and including a noticeable black eschar in the centre. The majority of ecthyma gangrenosum instances occur in immunocompromised individuals, such as those with significant underlying medical conditions or those who are neutropenic.
View Article and Find Full Text PDFCase Rep Dermatol
November 2024
Microbiology Program, School of Basic Sciences, Universidad Santiago de Cali, Cali, Colombia.
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