The connective tissues of the bovine optic nerve and left recurrent nerve have been investigated at the ultrastructure level by TEM and freeze-fracture. The outermost of three concentric sheaths enveloping the nerve appear very similar; the intermediate sheaths appear different enough to suggest different functionalities, while the innermost sheaths are completely dissimilar. The ultrastructural aspects of the extracellular matrix suggest that all the connective tissues may mainly play a passive role as a packing material for the nerve fibers, while none of the sheaths seems apt to withstand mechanical stresses.
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Cureus
December 2024
Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, New York, USA.
Marfan syndrome (MFS), an inherited connective tissue disorder, is caused by a mutation in the FBN1 gene. MFS is characterized by complex manifestations involving musculoskeletal, cardiovascular, and ocular systems. The usual presentation for suspecting diagnosis in an individual with aortic root disease is tall stature in addition to other features that fulfill Ghent criteria.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Departement of radiology HER, University Mohammed V Rabat, Rabat, Morocco.
We report the case of a 15-year-old girl who presented with a 2-month history of severe fatigue and rapidly worsening myalgia. Biological tests revealed hypereosinophilia and an inflammatory syndrome. MRI showed increased signal intensity in the superficial and deep aponeurotic layers on T2-weighted images, with moderate fascia enhancement after contrast administration.
View Article and Find Full Text PDFRev Med Suisse
January 2025
Centre pédiatrique de Meyrin, Rue de la Prulay 35, 1217 Meyrin.
Joint hypermobility is a common feature in children and adolescents, often physiological and benign, but it is also a manifestation of hereditary connective tissue disorders. In pediatrics, there is a real need to differentiate Ehlers-Danlos syndrome (EDS) hypermobile type (hEDS) from benign hypermobility, in the absence of a genetic marker specific to this form of EDS. In 2023, the International Ehlers-Danlos Consortium revised the diagnostic criteria for children and adolescents, introducing the concept of hypermobility spectrum disorder.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, No.41 Linyin Road, Baotou, Inner Mongolia, 014010, China.
The tendon-bone interface, known as the tenosynovial union or attachment, can be easily damaged by excessive exercise or trauma. Tendon-bone healing is a significant research topic in orthopedics, encompassing various aspects of sports injuries and postoperative recovery. Surgery is the most common treatment; however, it has limited efficacy in promoting tendon-bone healing and carries a risk of postoperative recurrence, necessitating the search for more effective treatments.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Mechanical Engineering, Centre for Mechanical Technology & Automation (TEMA), University of Aveiro, Aveiro, 3810-193, Portugal.
Background: Bone fractures represent a global public health issue. Over the past few decades, a sustained increase in the number of incidents and prevalent cases have been reported, as well as in the years lived with disability. Current monitoring techniques predominantly rely on imaging methods, which can result in subjective assessments, and expose patients to unnecessary cumulative doses of radiation.
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