Carpal tunnel syndrome (CTS) and cubital tunnel syndrome (Cub.TS) are the two most common entrapment syndromes. Development of several validated outcome assessments have allowed conducting large scale epidemiological studies worldwide for the last decade regarding CTS, which have been providing reliable basic information. These studies have shown that CTS is more common than had been expected. It is estimated that lifetime risk of acquiring CTS is 10%, the annual incidence is 0.1% among adults, and overall prevalence is 2.7% among the general population. The most common cause is idiopathic inflammation of the flexor tendon sheath induced by activities involving repetitive wrist movement. In contrast, they are not available for Cub.TS and most data are derived from case series or expert opinion, therefore, information concerning Cub.TS is less reliable. In this lecture, the author is trying to offer up-date information of these entrapment neuropathies regarding their pathophysiology, epidemiology, and tips & pitfalls of diagnosis and treatment.
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Tob Induc Dis
January 2025
Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Introduction: It is currently uncertain whether smoking is a risk factor for carpal tunnel syndrome (CTS). This study aims to elucidate association between smoking and CTS using Mendelian randomization (MR) analysis.
Methods: This study was a secondary analysis of publicly available GWAS data, using four smoking phenotypes (smoking initiation, smoking status, lifetime smoking, and never smoking) as exposures, and two CTS datasets (discovery and validation sets) as outcomes for MR analysis.
Med Clin (Barc)
January 2025
Servicio de Medicina Interna, Hospital Universitario Virgen de las Nieves, Granada, España.
Int Orthop
January 2025
Physical Medicine and Rehabilitation Division, Department of Orthopaedic Surgery, Stanford University, Redwood City, CA, USA.
Purpose: This narrative review identifies and summarizes current evidence for diagnostic ultrasonographic evaluation of upper extremity dynamic compressive neuropathies affecting athletes.
Methods: Relevant literature was identified using the PubMed database and then summarized.
Results: The compressive neuropathies affecting athletes we identified included: neurogenic thoracic outlet syndrome, pectoralis minor syndrome, quadrilateral space syndrome, suprascapular nerve entrapment, proximal median nerve entrapment or bicipital aponeurosis/lacertus fibrosus (lacertus syndrome), radial tunnel syndrome, and cubital tunnel syndrome.
Circ J
January 2025
Department of Cardiovascular Medicine, Osaka Metropolitan University Graduate School of Medicine.
Background: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an under-recognized cause of heart failure (HF) in older adults. Delayed ATTR-CM diagnosis may result in more advanced symptoms. This study describes the journey of Japanese patients with ATTR-CM.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Republic of Korea.
Objective: Cubital tunnel syndrome is a common peripheral neuropathy of the upper extremity. Anterior transposition of the ulnar nerve is an established surgical treatment option for this condition. This study aimed to introduce a novel musculofascial lengthening technique that uses only a portion of the flexor-pronator muscle mass for submuscular anterior transposition of the ulnar nerve and investigate its clinical outcomes.
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