AI Article Synopsis
- The study examined how low or high levels of serum thyrotropin (TSH) relate to mortality in patients with coronary artery disease who had undergone invasive treatments.
- Over a mean follow-up of 6.4 years with 942 patients, 12.5% had low TSH and 13.3% had high TSH, while 18.5% of the participants died during this period.
- Results showed that patients with either low or high TSH levels experienced lower overall and circulatory mortality compared to those whose TSH levels were within the normal range.
Article Abstract
The aim of the present study was to analyze the relation of low or high serum thyrotropin (TSH) with mortality in patients with invasively treated coronary artery disease. We followed-up 942 patients who underwent coronary angioplasties or coronary artery bypass graft surgery over a mean follow-up period of 6.4+/-1.6 years. The study population was divided into three groups using the reference limits of serum TSH (0.25-2.12 mIU/l) as cut-offs. There were 118 patients (12.5%) with low and 125 patients (13.3%) with high serum TSH. One hundred and seventy-four subjects (18.5%) deceased during follow-up. Multivariable analyses revealed that both subjects with low and high serum TSH had a lower all-cause and circulatory mortality than subjects with serum TSH within the reference range. We conclude that low and high serum TSH levels are associated with a reduced all-cause and circulatory mortality in patients with coronary artery disease.
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| http://dx.doi.org/10.1016/j.ijcard.2007.11.075 | DOI Listing |
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