AI Article Synopsis
- A study was conducted on 149 children with nighttime bedwetting to evaluate how effective alarm treatment is after using drugs or exercises to increase the amount of urine they could hold!* -
- The results showed that boosting maximum volume voided through exercises didn't significantly impact the success rates of the alarm treatment, which had response rates between 50% to 73% and cure rates from 50% to 67% overall!* -
- Factors like prior treatments and being younger than 8 years old appeared to be strong predictors of how effective the alarm treatment would be for those children.*
Article Abstract
Purpose: We prospectively assessed response and cure rates of alarm treatment, following pretreatment with antimuscarinics and/or holding exercises aimed at increasing maximum volume voided in 149 children with monosymptomatic nocturnal enuresis.
Materials And Methods: In a prior trial the same 149 children had been randomized into 5 groups to assess interventions for increasing maximum volume voided, namely placebo or antimuscarinics with (groups A and B, respectively) and without (C and D, respectively) holding exercises, and a control group (E) receiving just alarm treatment. Following pretreatment groups A to D received alarm treatment. Full response and cure rates were assessed, as well as the influence on these rates of baseline maximum volume voided, increase in maximum volume voided after pretreatment, gender, age and previous treatment.
Results: Neither full response nor cure was influenced significantly by the increase in maximum volume voided achieved in groups A and B with holding exercises. Overall full response ranged from 50% to 73%, and overall cure ranged from 50% to 67%. Possible predictors for full response and cure were prior treatment (p <0.02) and age younger than 8 years (p <0.05).
Conclusions: In monosymptomatic nocturnal enuresis increasing maximum volume voided does not affect response or cure rate of subsequent alarm treatment. Previous treatment and age younger than 8 years are possible predictors for response and cure.
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| http://dx.doi.org/10.1016/j.juro.2007.10.096 | DOI Listing |
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