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Results: In total, 4322 patients were admitted, and 435 samples for CDI were analyzed, with 104/435 (23.

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  • * It emphasizes the role of exotoxins produced by this pathogen as critical factors in causing infections and food poisoning in humans and animals, listing specific toxins associated with different illnesses, such as foodborne poisoning and toxic shock syndrome.
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Clostridioides (formerly Clostridium) difficile is the most important infectious cause of antibiotic-associated diarrhea worldwide and a leading cause of healthcare-associated infection in the United States. The incidence of C. difficile infection (CDI) in children has increased, with 20 000 cases now reported annually, also posing indirect educational and economic consequences.

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The increasing rate of community-associated (CA-SA) worldwide has aroused global public concern for decades. Although ST121 clone is one of the prevalent CA-SA in China, there is still limited knowledge about it. In this study, we conducted a genomic analysis of 28 CA-SA ST121 isolates from severe bloodstream infection cases and 175 ST121 isolates from the public database.

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