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Antenatal couples' counselling in Uganda (ACCU): study protocol for a randomised controlled feasibility trial.
Pilot Feasibility Stud
April 2022
School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
Background: Common avoidable factors leading to maternal, perinatal and neonatal deaths include lack of birth planning (and delivery in an inappropriate place) and unmet need for contraception. Progress has been slow because routine antenatal care has focused only on women. Yet, in Uganda, many women first want the approval of their husbands.
View Article and Find Full Text PDFTracer-Based Metabolic NMR-Based Flux Analysis in a Leukaemia Cell Line.
Chempluschem
May 2016
Institute of Cancer and Genomics Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
High levels of reactive oxygen species (ROS) have a profound impact on acute myeloid leukaemia cells and can be used to specifically target these cells with novel therapies. We have previously shown how the combination of two redeployed drugs, the contraceptive steroid medroxyprogesterone and the lipid-regulating drug bezafibrate exert anti-leukaemic effects by producing ROS. Here we report a C-tracer-based NMR metabolic study to understand how these drugs work in K562 leukaemia cells.
View Article and Find Full Text PDFContraception in the cosmos: the combined oral contraceptive pill in space.
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