We report on the optimization of a snapshot Mueller matrix polarimeter performed by using singular-value decomposition. The snapshot technique relies on wavelength polarization coding by four wave plates. The statistical noise on Mueller components is minimized through adjustment of the thickness of each plate. The spectrometer response and its cutoff frequency were considered to find the optimal configurations described here.
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http://dx.doi.org/10.1364/ol.33.000144 | DOI Listing |
bioRxiv
December 2024
University of Virginia, Department of Biology, Charlottesville, VA, USA.
Changes in the copy number of large genomic regions, termed copy number variations (CNVs), contribute to important phenotypes in many organisms. CNVs are readily identified using conventional approaches when present in a large fraction of the cell population. However, CNVs that are present in only a few genomes across a population are often overlooked but important; if beneficial under specific conditions, a de novo CNV that arises in a single genome can expand during selection to create a larger population of cells with novel characteristics.
View Article and Find Full Text PDFSensors (Basel)
December 2024
2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
The widespread propagation of wireless communication devices, from smartphones and tablets to Internet of Things (IoT) systems, has become an integral part of modern life. However, the expansion of wireless technology has also raised public concern about the potential health risks associated with prolonged exposure to electromagnetic fields. Our objective is to determine the optimal machine learning model for constructing electric field strength maps across urban areas, enhancing the field of environmental monitoring with the aid of sensor-based data collection.
View Article and Find Full Text PDFBiochem Biophys Res Commun
December 2024
Biophysics Institute, CNR-IBF, Via Corti 12, I-20133, Milano, Italy; Department of Bioscience, University of Milan, Via Celoria 26, I-20133, Milano, Italy. Electronic address:
Aldolases are crucial enzymes that catalyze the formation of carbon-carbon bonds in the context of the anabolic and catabolic pathways of various metabolites. The bacterium Pseudomonas fluorescens N3 can use naphthalene as its sole carbon and energy source by using, among other enzymes, the trans-o-hydroxybenzylidenepyruvate (tHBP) hydratase-aldolase (HA), encoded by the nahE gene. In this study, we present the crystallographic structures of tHBP-HA in three different functional states: the apo enzyme with a phosphate ion in the active site, and the Schiff base adduct bound either to pyruvate or to the substitute with '(R)-4-hydroxy-4-(2-hydroxyphenyl)-2-oxobutanoate'(intermediate state).
View Article and Find Full Text PDFCurr Neurol Neurosci Rep
January 2025
Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier University Medical Center, 80 Avenue Augustin Fliche, Montpellier, 34295, France.
Purpose Of Review: In low-grade glioma (LGG), besides the patient's neurological status and tumor characteristics on neuroimaging, current treatment guidelines mainly rely on the glioma's genetics at diagnosis to define therapeutic strategy, usually starting with surgical resection. However, this snapshot in time does not take into account the antecedent period of tumor progression and its interactions with the brain before presentation. This article reviews new concepts that pertain to reconstruct the history of previous interplay between the LGG's course and adaptive changes in the connectome within which the glioma is embedded over the years preceding the diagnosis.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Molecular Sensing and Imaging Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China.
Nanopore technology holds great potential for single-molecule identification. However, extracting meaningful features from ionic current signals and understanding the molecular mechanisms underlying the specific features remain unresolved. In this study, we uncovered a distinctive ionic current pattern in a K238Q aerolysin nanopore, characterized by transient spikes superimposed on two stable transition states.
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