Food safety has acquired great attention by food importer and exporters. Food rejection or acceptance across international borders is based on the compliance with international food regulations. Due to the lack of recent data on pesticide residues in Mexican grains, this study focused on detecting and quantifying insecticide residues in stored wheat, corn, chickpeas, and beans, as well as to determine their mutagenic potential. Grains were sampled from primary storage sites in Sonora, Mexico. Malathion, chlorpyrifos, deltamethrin, cypermethrin, 4,4-DDE, 4,4-DDD and 4,4-DDT were analyzed in 135 samples. Grain samples were not mutagenic and most pesticide levels were within regulation limits.
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http://dx.doi.org/10.1007/s00128-007-9302-8 | DOI Listing |
J Agric Food Chem
March 2025
Department of Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu 96822, Hawaii United States.
Autophagy-associated protein 8 (ATG8) is essential for autophagy and organismal growth and development. In this study, we successfully resolved the crystal structure of () ATG8a (ATG8a) at 1.36 Å resolution.
View Article and Find Full Text PDFLangmuir
March 2025
Co-Innovation Center for Efficient Processing and Utilization of Forest Products, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Pine wilt disease is caused by invasion and has a great impact on global pine resources. Injection of emamectin benzoate (EB) into pine trunks is an effective way to control . However, EB has limited aqueous solubility, easily photodissociates, and its long-term use causes resistance problems.
View Article and Find Full Text PDFJ Agric Food Chem
March 2025
College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.
Inwardly rectifying potassium channels (Kir) play a key role in regulating various physiological processes. However, the structural and pharmacological mechanisms of insect Kir channels remain unclear. In this study, we show that coexpression of different Kir subunits in the same tissue did not affect the rectification properties of strongly rectifying Kir.
View Article and Find Full Text PDFACS Omega
March 2025
Department of Chemistry, Georgia Gwinnett College, 1000 University Center Lane, Lawrenceville, Georgia 30043, United States.
Homology modeling can help bridge the gap between missing 3D structures and available primary sequences of protein. More environmentally friendlier insecticides against domestic nuisance can target the octopamine receptor proteins, only expressed in invertebrates. Herein, octopamine receptor homologues from and , which do not have tertiary structures in the Protein Data Bank (PDB), were built using homology modeling and evaluated with various molecular modeling tools.
View Article and Find Full Text PDFInt J Biol Macromol
March 2025
Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science; Key Laboratory of National Forestry and Grassland Administration on Pest Chemical Control, China Agricultural University, Beijing 100193, China. Electronic address:
Chitinases are recognized as potential targets to develop novel insecticides to control lepidopteran pests. However, the design and development of effective multi-chitinase inhibitors remains a huge challenge. Based on the backgrounds, in this study, we designed and synthesized a series of cinnamyl-thiazolidinedione compounds as potential inhibitors against OfChtI, OfChtII and OfChi-h, for the first time, by integrating strategies including fragment replacement, 3D QSAR-guided design, and bioelectronic isosteric replacement.
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