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[Vaccination against mouse pox].

Tierarztl Prax

January 1986

Attenuated MVA-strain of vaccinia virus has been efficient in the control of enzootic mousepox and in prophylactic vaccination. The virus has been used as a live vaccine for prophylactic and emergency vaccinations as well as for sanitation of populations. More than 100 000 vaccinations were carried out safely.

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Mousepox is an orthopoxvirus infection of mice that was discovered in laboratory mice in England in 1930. Depending upon mouse genotype, it may produce a severe disease with acute hepatitis and high mortality, a generalized rash in animals that survive longer, or a trivial inapparent infection. It has long been enzootic in breeding stocks of mice in Europe, Japan, and China but not in North America and Australia.

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