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Gastroprotective effect of fucoidan from Sargassum siliquastrum against ethanol-induced gastric mucosal injury.
Food Res Int
February 2025
SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, PR China; National & Local Joint Engineering Laboratory for Marine Bioactive Polysaccharide Development and Application, Dalian Polytechnic University, Dalian 116034, PR China. Electronic address:
The ethanol-induced BALB/c mice and human gastric epithelial cell (Ges-1 cell) models were used to investigate the Sargassum siliquastrum fucoidan (SFuc) gastroprotective capability. The injury score and histopathological sections of the stomach were used to evaluate the gastroprotective capability. The western blotting and RT-PCR methods determined the signaling mechanism of mice's gastric injury.
View Article and Find Full Text PDFAscaris lumbricoides a rare cause gastric perforation: a case report and brief literature review.
Front Med (Lausanne)
January 2025
Department of General Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei, China.
(AL), a prevalent nematode causing ascariasis, infects millions worldwide, with a higher risk in preschool and school-aged children. Though infections are usually mild, rare and life-threatening complications like gastrointestinal perforation exist. This article documents a case involving a 61-year-old deaf-mute man who presented with a month-long history of epigastric pain accompanied by nausea, anorexia, and constipation.
View Article and Find Full Text PDFAdvances and results in omental patch repair of gastrointestinal perforations: A narrative review.
Surg Pract Sci
December 2024
Medical School, Pontifical Catholic University of Ecuador, Quito, Ecuador.
Omental patch repair is a crucial surgical procedure for managing gastrointestinal perforations, particularly those associated with peptic ulcers, necessitating a detailed review of its effectiveness and outcomes. This literature review aims to assess current knowledge on omental patch repair, focusing on advancements in surgical techniques and patient outcomes. Major medical databases, including PubMed, Scopus, and Web of Science, were searched for relevant studies published between 2020 and 2024, prioritizing those that explored omental patch repair, surgical methods, and associated clinical outcomes.
View Article and Find Full Text PDFPeptic Ulcer Disease: A Comprehensive Review on Conventional Therapy and Herbal Treatment.
Curr Drug Discov Technol
January 2025
Global Research Institute of Pharmacy, Radaur, Yamuna Nagar, 135133, Haryana, India.
Still today, peptic ulcer disease (PUD) is a major digestive illness that affects millions of people around the world every year. This study looks at both traditional and herbal ways of treating PUD, focusing on how they work, how well they work, and whether they can work together. Pharmaceuticals like antibiotics, proton pump inhibitors (PPIs), and H2-receptor antagonists are common ways to treat the condition.
View Article and Find Full Text PDFMaternal Smoking Around Birth Is a Risk Factor for Gastrointestinal Diseases in Offspring: A Mendelian Randomization Study.
Dig Dis Sci
January 2025
Department of Gastric and Colorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Background: The effect of maternal smoking around birth (MSAB) on gastrointestinal (GI) diseases in the offspring is still not fully understood.
Aim: We conducted a rigorous Mendelian randomization (MR) study to examine the association between MSAB and 24 GI diseases in offspring.
Methods: Single nucleotide polymorphisms (SNPs) associated with MSAB were obtained from a recent study.
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