We discuss the design and implementation of forward-imaging instruments for optical coherence tomography (OCT), which require the delivery, scanning, and collection of single-spatial-mode optical radiation. A hand-held surgical probe for use in open surgery can provide cross-sectional images of subsurface tissue before surgical incisions are made. A rigid laparoscope for minimally invasive surgical OCT imaging provides a simultaneous enface view of the area being imaged. OCT imaging is demonstrated on in vitro human specimens.
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http://dx.doi.org/10.1364/ol.22.001618 | DOI Listing |
Cardiovasc Eng Technol
April 2024
Mechanical Engineering Department, University of Washington, Seattle, WA, USA.
Purpose: Intravascular endoscopy can aid in the diagnosis of coronary atherosclerosis by providing direct color images of coronary plaques. The procedure requires a blood-free optical path between the catheter and plaque, and achieving clearance safely remains an engineering challenge. In this study, we investigate the hemodynamics of saline flushing in partially occluded coronary arteries to advance the development of intravascular forward-imaging catheters that do not require balloon occlusion.
View Article and Find Full Text PDFAnalyst
February 2020
Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4L, 1090 Vienna, Austria.
J Biophotonics
April 2019
Gisela and Erwin Sick Chair of Micro-optics, Department of Microsystems Engineering, University of Freiburg, Freiburg, Germany.
Photonics
September 2014
Vanderbilt Eye Institute, Vanderbilt University, Nashville, TN 37232-8808, USA.
Real-time intraoperative B-scan optical coherence tomography (OCT) visualization of intraocular tissues is a desired ophthalmic feature during retinal procedures. A novel intraocular 25-gauge B-mode forward-imaging OCT probe was combined with a 36-gauge needle into a prototype instrument. Imaging of the needle tip itself and the effects of saline injection into a gelatin phantom were performed.
View Article and Find Full Text PDFBiomed Opt Express
February 2015
Vanderbilt Eye Institute, Vanderbilt University 2311 Pierce Avenue Nashville, TN 37232, USA ; Vanderbilt Initiative in Surgery and Engineering(ViSE), Vanderbilt University 2525 West End Avenue, 6th Floor, Nashville, TN 37203, USA ; Vanderbilt Biomedical Photonics Laboratories, Vanderbilt University 100 Keck FEL Center, Nashville, TN 37203, USA.
Real-time intraocular optical coherence tomography (OCT) visualization of tissues with surgical feedback can enhance retinal surgery. An intraocular 23-gauge B-mode forward-imaging co-planar OCT-forceps, coupling connectors and algorithms were developed to form a unique ophthalmic surgical robotic system. Approach to the surface of a phantom or goat retina by a manual or robotic-controlled forceps, with and without real-time OCT guidance, was performed.
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