Tetanus in an injecting buprenorphine abuser.

Ann Acad Med Singap

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.

Published: December 2007

Introduction: Injecting drug abusers are vulnerable to many infectious complications. We describe a case of tetanus in a Singaporean who regularly abused buprenorphine.

Clinical Picture: A 49-year-old male was hospitalised for progressive generalised spasms associated with dysarthria and opisthotonus. Tetanus was diagnosed clinically.

Treatment: Supportive management was instituted in the intensive care unit (ICU). Toxicology samples tested positive for buprenorphine.

Outcome: He recovered rapidly and was transferred out of the ICU after 8 days. Retrospective questioning confirmed parenteral abuse of buprenorphine.

Conclusion: This case highlights an uncommon and potentially lethal complication of parenteral drug abuse.

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