Objective: To investigate the expression of alpha-smooth muscle action (alpha-SMA) in the renal tubulointerstitium in patients with kidney collateral stasis.
Methods: The expression of alpha-SMA in the renal biopsy specimens from 54 patients with kidney collateral stasis was examined by immunohistochemical method.
Results: The degree of kidney collateral stasis was increased with the increasing of the degree of renal interstitial fibrosis (P<0.05), and there was significant positive correlation between kidney collateral stasis and alpha-SMA expression (P<0.05).
Conclusion: Kidney collateral stasis is one of the main reasons of renal fibrosis. With the increasing of kidney collateral stasis, MFBs in the renal interstitium proliferate obviously, becoming one of the most important causes of renal interstitial fibrosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3736/jcim20080109 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Little strokes fell big oaks: The use of weak magnetic fields and reactive oxygen species to fight cancer.
Redox Biol
December 2024
Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, P.O. Box 3000, 90014, Oulu, Finland.
The increase in early-stage cancers, particularly gastrointestinal, breast and kidney cancers, has been linked to lifestyle changes such as consumption of processed foods and physical inactivity, which contribute to obesity and diabetes - major cancer risk factors. Conventional treatments such as chemotherapy and radiation often lead to severe long-term side effects, including secondary cancers and tissue damage, highlighting the need for new, safer and more effective therapies, especially for young patients. Weak electromagnetic fields (WEMF) offer a promising non-invasive approach to cancer treatment.
View Article and Find Full Text PDF[Scientific connotation of Zangfu theory in traditional Chinese medicine from modern biological research on "organ crosstalk"].
Zhongguo Zhong Yao Za Zhi
November 2024
Center for Evidence-based Chinese Medicine, Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Beijing 100700, China.
Life is a dynamic and systematic whole, with organs interacting with each other. Traditional Chinese medicine(TCM) discusses the interaction between human tissue and organs through the Zangfu relations, while modern biological medicine clarifies physiological and pathological relationships through "organ crosstalk". From the perspective of "organ crosstalk", this article discussed the five classical Zangfu relations(lungs and large intestine, heart and small intestine, spleen and stomach, liver and gallbladder, and kidney and bladder) in TCM and their extension.
View Article and Find Full Text PDFLong-term efficacy of subclavian vein stenting in a patient on hemodialysis complicated by stasis dermatitis due to subclavian vein stenosis.
J Cardiol Cases
December 2024
Department of Cardiology, Japanese Red Cross Ashikaga Hospital, Ashikaga, Japan.
Unlabelled: Data about the long-term safety and efficacy of stent implantation for central venous stenosis in patients on dialysis are limited. We report the case of a 66-year-old man on hemodialysis for end-stage renal disease who presented with stasis dermatitis around an arteriovenous shunt with ulceration of the left forearm. Computed tomography angiography showed a tight stenosis of the proximal left subclavian vein and the development of collateral blood vessels around the stenosis.
View Article and Find Full Text PDFConcomitant, Acquired Cavo-Azygos Shunt and Spleno-Gastroepiploic Bypass After Multiple Venous Obstruction in a Dog.
Vet Med Sci
January 2025
Department of Veterinary Medical Imaging, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeollabuk-do, Republic of Korea.
A 13-year-old intact female Shih Tzu presented with anorexia, panting and pain of unknown origin. Physical examination was normal except for a systolic murmur (grade 3/6). Abdominal radiographs revealed an ill-defined area of increased opacity in the mid-abdomen.
View Article and Find Full Text PDFRetrograde filling of an internal iliac artery aneurysm via the profunda femoris artery: A case report of type IIa endoleak.
Int J Surg Case Rep
November 2024
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Introduction: Internal iliac artery aneurysms (IIAAs) are an uncommon but clinically significant vascular condition that can lead to life-threatening complications, such as rupture and endoleaks, following endovascular repair. Endoleaks particularly type IIa, occur when there is retrograde flow into the aneurysm sac from collateral vessels, and their presence can jeopardize the success of repair procedures. This case report illustrates a rare occurrence of a type IIa endoleak attributed to retrograde filling from the profunda femoris artery, providing insights into the diagnostic complexities and management of IIAAs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!