Unlabelled: The objective of this study was to determine frequency of admission hyperglycemia and abnormal glucose tolerance at discharge in patients with acute myocardial infarction and no previous history of diabetes mellitus.
Methods And Results: Data on 1522 patients with acute myocardial infarction and no previous history of diabetes mellitus were analyzed. Before discharge from hospital, standardized oral glucose tolerance test was performed in 197 patients with admission hyperglycemia.
Results: Admission hyperglycemia (> or =6.1 mmol/L) was determined in half of the patients with acute myocardial infarction: glucose concentration of 6.1-6.99 mmol/L was in 21.5% and > or =7.0 mmol/L in 30.1% of the patients. By using glucose tolerance test, normal glucose metabolism was noted in 57.9% of the patients with admission hyperglycemia; abnormal glucose tolerance was diagnosed newly in more than one-third and glucose concentration of > or =11.1 mmol/L in 10.1% of the patients.
Conclusions: Abnormal glucose tolerance is a frequent feature in nondiabetic patients with admission hyperglycemia during acute myocardial infarction, and glucose tolerance test should be considered in all patients with ischemic heart disease for early modification of this risk factor.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of Kentucky, Lexington, KY, USA.
Background: Alzheimer's disease is defined by the pathological aggregation of amyloid-beta and hyperphosphorylated tau. AD patients often exhibit other symptoms like metabolic and sleep dysfunction. Currently, it is unclear if impairments are a cause or consequence of Aβ or tau aggregation.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of Oregon, Eugene, OR, USA.
Background: Postmenopausal females who carry an APOE4 allele are at higher risk of late-onset Alzheimer's Disease (LOAD) compared to age-matched APOE4 males. Estrogen deficiency predisposes females to an increased risk of vascular, cognitive and metabolic impairments. Estrogen and APOE genotype are known to impact metabolic and mitochondrial function in the brain, but their effects on cerebral vessels are unknown.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
Nova Southeastern University, Fort Lauderdale, FL, USA.
Background: Cerebral amyloid angiopathy (CAA), characterized by the accumulation of amyloid protein in the cerebral vasculature, is highly prevalent in Alzheimer's disease (AD) patients and, on its own, increases the risk of hemorrhagic stroke, cognitive impairment, and dementia. Currently, there are no effective ways to treat or prevent CAA. Ketogenic diet (KD), characterized by high-fat, low-carbohydrate, and moderate amounts of protein consumption, has gained considerable attention in recent years for its potential therapeutic use in patients with neurodegenerative diseases, including Alzheimer's disease.
View Article and Find Full Text PDFRelationship between vitamin D deficiency and gestational diabetes: a narrative review.
Front Endocrinol (Lausanne)
January 2025
Department of Endocrinology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Vitamin D, often referred to as the "sunshine vitamin," is an essential fat-soluble vitamin that plays a critical role in bone health and has been shown to improve insulin sensitivity and glucose tolerance. Vitamin D deficiency is prevalent among pregnant and pre-pregnancy women, which increases the risk of developing gestational diabetes mellitus (GDM), a common complication during pregnancy. Recent studies have explored various aspects of the relationship between vitamin D deficiency and GDM, including the mechanisms by which vitamin D affects glucose metabolism, the role of the vitamin D receptor gene, and the impact of routine vitamin D supplementation before and during pregnancy.
View Article and Find Full Text PDFThe appropriate nutrient conditions for methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilm formation in vitro.
Sci Rep
January 2025
Department of Biological and Medical Sciences, Charles University, Faculty of Pharmacy in Hradec Králové, 2089, Zborovská, Hradec Králové, 500 03, Czech Republic.
Polymicrobial biofilms, the reason for most chronic wound infections, play a significant role in increasing antibiotic resistance. The in vivo effectiveness of the new anti-biofilm therapy is conditioned by the profound evaluation using appropriate in vitro biofilm models. Since nutrient availability is crucial for in vitro biofilm formation, this study is focused on the impact of four selected cultivation media on the properties of methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilms.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!