This article proposes 2 new approaches to test a nonzero population correlation (rho): the hypothesis-imposed univariate sampling bootstrap (HI) and the observed-imposed univariate sampling bootstrap (OI). The authors simulated correlated populations with various combinations of normal and skewed variates. With alpha set=.05, N> or =10, and rho< or =0.4, empirical Type I error rates of the parametric r and the conventional bivariate sampling bootstrap reached .168 and .081, respectively, whereas the largest error rates of the HI and the OI were .079 and .062. On the basis of these results, the authors suggest that the OI is preferable in alpha control to parametric approaches if the researcher believes the population is nonnormal and wishes to test for nonzero rhos of moderate size.
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http://dx.doi.org/10.1037/1082-989X.12.4.414 | DOI Listing |
Schizophr Bull
December 2024
Department of Psychiatry, Affiliated Brain Hospital of Nanjing Medical University, Nanjing, 210029, China.
Background And Hypothesis: Respective abnormal structural connectivity (SC) and functional connectivity (FC) have been reported in individuals with schizophrenia. However, transmodal associations between SC and FC following antipsychotic treatment, especially in female schizophrenia, remain unclear. We hypothesized that increased SC-FC coupling may be found in female schizophrenia, and could be normalized after antipsychotic treatment.
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemistry, University of Alberta, Edmonton, AB T6G 2G2, Canada.
Genetically encoded libraries (GEL) are increasingly being used for the discovery of ligands for "undruggable" targets that cannot be addressed with small molecules. Foundational GEL platforms like phage-, yeast-, ribosome-, and mRNA-display have enabled the display of libraries composed of 20 natural amino acids (20AA). Unnatural amino acids (UAA) and chemical post-translational modification (cPTM) expanded GEL beyond the 20AA space to yield unnatural linear, cyclic, and bicyclic peptides.
View Article and Find Full Text PDFJ Vasc Surg Venous Lymphat Disord
December 2024
Department of Radiology, Beijing Shijitan Hospital, Capital Medical University, China. Electronic address:
Purpose: According to International Lymphology Society guidelines, the severity of lymphedema is determined by the difference in volume between the affected limb and the healthy side divided by the volume of the healthy side. However, this method of measuring volume is time-consuming, laborious, and has certain errors in clinical applications.Therefore, this study aims to explore whether machine learning radiomics features based on non-contrast magnetic resonance imaging (NCMRI) can predict the severity of primary lower limb lymphedema.
View Article and Find Full Text PDFPLoS One
December 2024
Behavioural and Social Sciences, University of Groningen, Groningen, the Netherlands.
Background: The importance of replication in the social and behavioural sciences has been emphasized for decades. Various frequentist and Bayesian approaches have been proposed to qualify a replication study as successful or unsuccessful. One of them is meta-analysis.
View Article and Find Full Text PDFJ Comput Assist Tomogr
December 2024
From the Department of Radiology.
Aim: This study aimed to analyze the differences in radiomic features of the anterior scalene muscle and evaluate the diagnostic performance of MRI-based radiomics model for neurogenic thoracic outlet syndrome (NTOS).
Materials And Methods: Imaging data of patients with NTOS who underwent preoperative brachial plexus magnetic resonance neurography were collected and were randomly divided into training and test groups. The anterior scalene muscle area was sliced in the T1WI sequence as the region of interest for the extraction of radiomics features.
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