The quality of life of cancer relatives should influence the justification, selection, and modification of nursing interventions in the cancer patient-family dyad. To justify these interventions, relevant, valid, and reliable quality of life assessments are needed. The purpose of this study was to examine the relevancy, validity, and reliability of the World Health Organization Quality of Life Instrument-BREF in a sample of 435 Norwegian cancer relatives. The World Health Organization Quality of Life Instrument-Short Form is a multidimensional, generic instrument designed for the assessment of quality of life cross-culturally. Cronbach alpha ranged from .59 in the social domain to .86 in the psychological domain. Correlational analysis confirmed the relevancy of the items and domains and lent partial support to the construct validity of the scale. Multivariate analyses showed that all domains were significant explanatory variables for overall quality of life and health satisfaction with the exception of the environmental domain. Subgroups effects were best shown by the physical domain. Factor analysis resulted in a 4-factor solution, with 24 items explaining 57% of the cumulative variance in this sample. Results of a confirmatory factor analyses showed reasonably good fit indices, although several covariates between the residuals had to be added, and the covariates between the factors were high. The World Health Organization Quality of Life Instrument-BREF has been translated into 40 languages. It is hoped that cancer nurses will continue to test the instrument in various groups of relatives so that scale validity and conceptual clarity can be improved and subgroup interactions confirmed.
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http://dx.doi.org/10.1097/01.NCC.0000305678.21390.f4 | DOI Listing |
J Dev Phys Disabil
January 2024
School of Rehabilitation Therapy, Queen's University, Louise D. Acton Building, 31 George Street, Kingston, ON K7L 3N6 Canada.
Evidence suggests that integrated support, combining both natural and formal supports, is often essential for individuals with developmental disabilities to achieve their preferred quality of life. However, studies are limited on how to organize supports so that people with developmental disabilities and their families find a balance between formal and natural supports. Often, there are systemic and personal boundaries around the nature and extent of support that can be offered to persons with developmental disabilities through formal mechanisms, yet the value of natural supports in the lives of persons with developmental disabilities is often undervalued in society.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Introduction: When implemented by national and regional regulatory agencies good review practices (GRevPs) support the timely high-quality review of medicines for enhanced patients' availability to safe, quality and efficacious innovative and generic products. It is important that all aspects of GRevPs are continuously evaluated and updated to promote the continuous improvement of regulatory systems at national and regional levels. The aim of this study was to assess and compare the GRevPs of the national medicines regulatory agencies (NMRAs) of Burkina Faso, Cote d'Ivoire, Ghana, Nigeria, Senegal, Sierra Leone and Togo, who are active participants of the ECOWASMRH initiative to identify opportunities for improvement.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Xuanwu Hospital, Capital Medical University, Beijing, China.
Purpose: To study the effects of breathing exercises on preventing pulmonary complications in patients undergoing coronary artery bypass graft surgery.
Methods: Observing whether preoperative breathing exercises can reduce the incidence of postoperative pulmonary complications in patients undergoing coronary artery bypass graft surgery; observing whether these exercises can improve postoperative arterial oxygen pressure, oxygen saturation, and the distance walked in a six-minute walk test after surgery; as well as reduce hospital stay duration, lower treatment costs, and improve the quality of life as measured by the Short Form-36 Health Survey (SF-36).
Design: The study population includes patients undergoing coronary artery bypass graft surgery under general anesthesia; the research center is Capital Medical University Xuanwu Hospital; the sample size is 120.
Burns Trauma
January 2025
Department of Arthroscopic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Xuhui District, Shanghai 200233, China.
Objective: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that significantly impairs muscle regeneration following injuries, contributing to numerous complications and reduced quality of life. There is an urgent need for therapeutic strategies that can enhance muscle regeneration and alleviate these pathological mechanisms. In this study, we evaluate the therapeutic efficacy of W-GA nanodots, which are composed of gallic acid (GA) and tungstate (W6+), on muscle regeneration in type 2 diabetes mellitus (T2D)-induced muscle injury, with a focus on their anti-inflammatory and antioxidative effects.
View Article and Find Full Text PDFPak J Med Sci
January 2025
Khalid Rehman Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.
Objective: To determine the impact of leishmaniasis on the quality of life of patients visiting the district headquarter hospital in District Khyber, Khyber Pakhtunkhwa, Pakistan.
Methods: A cross-sectional exploratory study was conducted in District Headquarter Hospital of Khyber District, Khyber Pakhtunkhwa from November 2019 to April 2020. In this study, 349 participants who consented were included by using a non-probability consecutive sampling technique.
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