Two new chromane type meroterpenoids were isolated from the methanolic extract of the brown alga, Sargassum micracanthum. Their structures were elucidated based on spectroscopic analysis and chemical conversion. The absolute stereochemistry of the methyl group at C-8' in 1 and related compounds were determined by modified Mosher's method.
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http://dx.doi.org/10.1248/cpb.56.124 | DOI Listing |
Chem Biodivers
January 2025
Yantai Institute of Coastal Zone Research, Coastal biology and Bioresource Utilization, 17 Chunhui Road, 264003, Yantai, CHINA.
The fungal genus Fusarium is a treasure-trove of structurally diverse secondary metabolites, contributed greatly by marine-derived strains. A new cedrane sesquiterpene, fusacedrol (1), and a new fusarin member, fusarin M (2), were isolated from F. graminearum 12Ⅱ2N that was isolated as an endophyte from the marine brown alga Sargassum sp.
View Article and Find Full Text PDFMar Drugs
January 2025
Division of Functional Food Research, Korea Food Research Institute, Wanju-gun 55365, Republic of Korea.
(), an edible brown alga, is rich in isophloroglucin A (IPA) phlorotannin compounds and is effective in preventing diseases, including diabetes. We evaluated its anti-glycation ability, intracellular reactive oxygen species scavenging activity, inhibitory effect on the accumulation of intracellular MGO/MGO-derived advanced glycation end products (AGE), and regulation of downstream signaling pathways related to the AGE-receptor for AGEs (RAGE) interaction. IPA (0.
View Article and Find Full Text PDFMar Drugs
January 2025
Institute of Nutrition and Food Technology 'José Mataix', Biomedical Research Center, University of Granada, 18071 Granada, Spain.
The optimization of bioactive compound extraction from using ultrasound-assisted extraction (UAE) via sonotrode was investigated to maximize phenolic recovery and antioxidant activity while promoting a sustainable process. Optimal conditions (40% / ethanol in water, 38 min, 36% amplitude) were selected to maximize phenolic recovery while considering environmental and energy sustainability by optimizing extraction efficiency and minimizing solvent and energy usage. HPLC-ESI-QTOF-MS analysis tentatively identified 25 phenolic compounds, including sulfated phenolic acids, phlorotannins, flavonoids, and halophenols, with some reported for the first time in , underscoring the complexity of this alga's metabolome.
View Article and Find Full Text PDFChemosphere
January 2025
Plant Morphogenesis and Biochemistry Laboratory, Federal University of Santa Catarina, P. O. Box 476, 88049-900, Florianopolis, SC, Brazil. Electronic address:
The effect of the in vitro acute exposure to diesel oil (0.001%, 0.01%, 0.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Food Technology Division, ceiA3, CIAMBITAL, University of Almeria, 04120 Almeria, Spain.
is an invasive brown macroalga that has recently proliferated in the western Mediterranean Sea, causing significant environmental challenges. This alga, however, contains valuable bioactive compounds-alginate, mannitol, and phlorotannins-that can serve as biofertilizers to promote plant growth and aid in bioremediation of degraded or contaminated soils. This study focused on optimizing the extraction of these compounds from , transforming an ecological issue into a beneficial resource.
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