With some papers from "Société anonyme des eaux minérales du Breuil et du Broc's archives, the authors explain the difficults beginnings of Hydroxydase, by Louis Tixier, a pharmacist.
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Distinct Substrates of Idiopathic Ventricular Fibrillation Revealed by Arrhythmia Characteristics on Implantable Cardioverter-Defibrillator.
JACC Clin Electrophysiol
September 2024
IHU Liryc, Electrophysiology and Heart Modeling Institute, Foundation Bordeaux Université, Bordeaux, France; Cardiac electrophysiology and stimulation, Cardiology Department, Bordeaux University Hospital (CHU), Pessac, France.
Background: Idiopathic ventricular fibrillation (IVF) can be associated with undetected distinct conditions such as microstructural cardiomyopathic alterations (MiCM) or Purkinje (Purk) activities with structurally normal hearts.
Objectives: This study sought to evaluate the characteristics of recurrent VF recorded on implantable defibrillator electrograms, associated with these substrates.
Methods: This was a multicenter collaboration study.
Interobserver variability in target definition for stereotactic arrhythmia radioablation.
Front Cardiovasc Med
September 2023
Department of Cardiology, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.
Background: Stereotactic arrhythmia radioablation (STAR) is a potential new therapy for patients with refractory ventricular tachycardia (VT). The arrhythmogenic substrate (target) is synthesized from clinical and electro-anatomical information. This study was designed to evaluate the baseline interobserver variability in target delineation for STAR.
View Article and Find Full Text PDFJoint EANM/SNMMI guideline on radiomics in nuclear medicine : Jointly supported by the EANM Physics Committee and the SNMMI Physics, Instrumentation and Data Sciences Council.
Eur J Nucl Med Mol Imaging
January 2023
LaTIM, INSERM, UMR 1101, Univ Brest, Brest, France.
Purpose: The purpose of this guideline is to provide comprehensive information on best practices for robust radiomics analyses for both hand-crafted and deep learning-based approaches.
Methods: In a cooperative effort between the EANM and SNMMI, we agreed upon current best practices and recommendations for relevant aspects of radiomics analyses, including study design, quality assurance, data collection, impact of acquisition and reconstruction, detection and segmentation, feature standardization and implementation, as well as appropriate modelling schemes, model evaluation, and interpretation. We also offer an outlook for future perspectives.
Effect of Recombinant Gonadotropin on Testicular Function and Testicular Sperm Extraction in Five Cases of () Pathogenic Variants.
Front Endocrinol (Lausanne)
April 2022
Service de Biochimie et Biologie Moléculaire, UM Pathologies Endocriniennes, CR DEV-GEN, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Bron, France.
Background: pathogenic variants can cause congenital adrenal hypoplasia or primary adrenal insufficiency in early childhood usually associated with hypogonadotropic hypogonadism. is necessary for organogenesis of the adrenal cortex and to maintain normal spermatogenesis. In humans, restoration of fertility in patients carrying pathogenic variants is challenging.
View Article and Find Full Text PDFKiller whale genomes reveal a complex history of recurrent admixture and vicariance.
Mol Ecol
July 2019
Marine Mammal and Turtle Division, National Marine Fisheries Service, National Oceanographic and Atmospheric Administration, Southwest Fisheries Science Center, La Jolla, California.
Reconstruction of the demographic and evolutionary history of populations assuming a consensus tree-like relationship can mask more complex scenarios, which are prevalent in nature. An emerging genomic toolset, which has been most comprehensively harnessed in the reconstruction of human evolutionary history, enables molecular ecologists to elucidate complex population histories. Killer whales have limited extrinsic barriers to dispersal and have radiated globally, and are therefore a good candidate model for the application of such tools.
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