Is expensive and not evidence based
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| http://dx.doi.org/10.1136/bmj.39406.449456.BE | DOI Listing |
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Deprescribing of proton pump inhibitors in older patients: A cost-effectiveness analysis.
PLoS One
October 2024
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
Over-prescribing of proton-pump inhibitors (PPIs) is widely observed in older patients. Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. We aimed to examine the cost-effectiveness of PPI deprescribing service from the perspective of Hong Kong public healthcare provider.
View Article and Find Full Text PDFImproving the feasibility of deprescribing proton pump inhibitors: GPs' insights on barriers, facilitators, and strategies.
Front Pharmacol
September 2024
Department of Social Pharmacy, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Article Synopsis
- The overuse of proton pump inhibitors (PPIs) by GPs raises health concerns, highlighting the need for deprescribing strategies to address this issue.
- A qualitative study with nine GPs revealed four key themes regarding deprescribing: inappropriate prescribing practices, facilitators for deprescribing, barriers like time constraints and patient hesitance, and overall feasibility.
- GPs advocate for a collaborative and multi-faceted approach to make deprescribing more effective, including better guidelines, improved digital tools, and increased awareness among patients and healthcare providers.
Intake of Proton Pump Inhibitors Is Associated with a Shorter Time to First Treatment in Early-Stage Chronic Lymphocytic Leukemia.
Acta Haematol
September 2024
Department of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Introduction: Proton pump inhibitors (PPIs) are one of the most widely used drugs worldwide [Gut Liver. 2017;11(1):27-37]. The use of PPI has become a common practice and is overprescribed for all patients with cancer including patients with hematological malignancies.
View Article and Find Full Text PDF[Deprescribing proton pump inhibitors : what are the clinical practice guidelines ?].
Rev Med Suisse
September 2024
Service de médecine interne, Hôpital de La Tour, 1217 Meyrin/Genève.
Proton pump inhibitors (PPIs) are frequently overprescribed and maintained without clear indication, leading to significant clinical and economic consequences. Deprescribing, which involves discontinuing or reducing the dose of a medication, lacks clear guidelines for PPIs, despite various approaches being described. Gradual tapering of PPIs appears to be an effective strategy, especially when combined with non-pharmacological measures and multimodal interventions.
View Article and Find Full Text PDFThe cost of potentially inappropriate medications for older adults in Canada: A comparative cross-sectional study.
J Am Geriatr Soc
November 2024
Canadian Medication Appropriateness and Deprescribing Network, Centre de Recherche, Institut Universitaire de Gériatrie de Montréal, Montréal, Quebec, Canada.
Background: Potentially inappropriate medications (PIMs) are medications whereby the harms may outweigh the benefits for a given individual. Although overprescribed to older adults, their direct costs on the healthcare system are poorly described.
Methods: This was a cross-sectional study of the cost of PIMs for Canadians aged 65 and older, using adapted criteria from the American Geriatrics Society.
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