We used authentication tests developed for ancient DNA to evaluate claims by Asara et al. (Reports, 13 April 2007, p. 280) of collagen peptide sequences recovered from mastodon and Tyrannosaurus rex fossils. Although the mastodon samples pass these tests, absence of amino acid composition data, lack of evidence for peptide deamidation, and association of alpha1(I) collagen sequences with amphibians rather than birds suggest that T. rex does not.
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| http://dx.doi.org/10.1126/science.1147046 | DOI Listing |
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Comment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".
Science
August 2008
Department of Computer Science and Engineering, University of California, San Diego, 9500 Gilman Drive, Mail Code 0404, La Jolla, CA 92093-0404, USA.
Asara et al. (Reports, 13 April 2007, p. 280) reported sequencing of Tyrannosaurus rex proteins and used them to establish the evolutionary relationships between birds and dinosaurs.
View Article and Find Full Text PDFMolecular phylogenetics of mastodon and Tyrannosaurus rex.
Science
April 2008
Harvard University, Cambridge, MA 02138, USA.
We report a molecular phylogeny for a nonavian dinosaur, extending our knowledge of trait evolution within nonavian dinosaurs into the macromolecular level of biological organization. Fragments of collagen alpha1(I) and alpha2(I) proteins extracted from fossil bones of Tyrannosaurus rex and Mammut americanum (mastodon) were analyzed with a variety of phylogenetic methods. Despite missing sequence data, the mastodon groups with elephant and the T.
View Article and Find Full Text PDFComment on "Protein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry".
Science
January 2008
BioArch, Departments of Biology, Archaeology, Chemistry and Technology Facility, University of York, Post Office Box 373, York YO10 5YW, UK.
We used authentication tests developed for ancient DNA to evaluate claims by Asara et al. (Reports, 13 April 2007, p. 280) of collagen peptide sequences recovered from mastodon and Tyrannosaurus rex fossils.
View Article and Find Full Text PDFProtein sequences from mastodon and Tyrannosaurus rex revealed by mass spectrometry.
Science
April 2007
Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
Fossilized bones from extinct taxa harbor the potential for obtaining protein or DNA sequences that could reveal evolutionary links to extant species. We used mass spectrometry to obtain protein sequences from bones of a 160,000- to 600,000-year-old extinct mastodon (Mammut americanum) and a 68-million-year-old dinosaur (Tyrannosaurus rex). The presence of T.
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