Groove pancreatitis is a rare form of chronic pancreatitis in which scarring is found mainly in the groove between the head of the pancreas, duodenum, and common bile duct. The pathogenesis of groove pancreatitis is still unclear but seems to be caused by the disturbance of pancreatic outflow through Santorini duct. It is often difficult to differentiate preoperatively between groove pancreatitis and pancreatic head carcinoma. Whereas conservative management is effective, some patients with duodenal obstruction may undergo Whipple's operation. A few cases of groove pancreatitis have been reported in Korea, and they were diagnosed only by clinical and radiological features. We experienced a case of groove pancreatitis who needed a surgical management because of severe duodenal obstruction. We report the case with a review of its characteristic pathologic findings.
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Clin J Gastroenterol
November 2024
Division of Hepato-Biliary-Pancreatic Surgery, Department of Gastroenterological Surgery, Toranomon Hospital, 2-2-2 Toranomon, Minato-Ku, Tokyo, 105-8470, Japan.
Ann Gastroenterol
October 2024
First Department of Medicine, University Hospital of Erlangen, Germany (Francesco Vitali, Deike Strobel, Sebastian Zundler, Markus F. Neurath, Dane Wildner).
Background: Paraduodenal pancreatitis (PP) is an inflammation involving the groove zone, delimited by the duodenum lumen, bile duct, and the head of the pancreas. This area may also be involved during acute pancreatitis (AP). The differential diagnosis is clinically relevant, since PP generally persists, whereas AP resolves.
View Article and Find Full Text PDFBiomaterials
April 2025
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:
Transplantation of insulin-secreting cells provides a promising method for re-establishing the autonomous blood glucose control ability of type 1 diabetes (T1D) patients, but the low survival of the transplanted cells hinder the therapeutic efficacy. In this study, we 3D-printed an encapsulation system containing β-like cells and microvascular fragments (MVF), to create a retrivable microdevice with vascularized islets in vivo for T1D therapy. The functional β-like cells were differentiated from the urine epithelial cell-derived induced pluripotent stem cells (UiPSCs).
View Article and Find Full Text PDFInt J Surg Case Rep
October 2023
Department of Surgery, Faculty of Medicine, University of Jaffna, Sri Lanka.
Introduction: Groove pancreatitis (GP) is a rare pancreatitis variant affecting the pancreaticoduodenal groove. It typically affects middle-aged men with a history of chronic alcoholism. Diagnosis is often challenging due to its resemblance with the head of the pancreatic carcinoma.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
The Key Laboratory of the Inorganic Molecule-based Chemistry of Liaoning Province and Laboratory of Coordination, College of Science, Shenyang University of Chemical Technology, Shenyang 110142, China; College of Environmental and Safety Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, China. Electronic address:
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