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| http://dx.doi.org/10.3174/ajnr.A0889 | DOI Listing |
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Altered brain glucose metabolism in COVID-19 disease: an activation likelihood estimation meta-analysis of PET studies.
Brain Imaging Behav
January 2025
School of Medicine, Pusan National University, Yangsan, Republic of Korea.
COVID-19 disease, caused by the SARS-CoV-2 virus, has significantly altered modern society and lifestyles. We investigated its impact on brain glucose metabolism by meta-analyzing existing studies that utilized 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) scans of the brain. We conducted a systematic search of MEDLINE and EMBASE databases from inception to August 2024 for English-language publications using the keywords "positron emission tomography", and "COVID-19".
View Article and Find Full Text PDFLipid Deposition in Skeletal Muscle Tissues and Its Correlation with Intra-Abdominal Fat: A Pilot Investigation in Type 2 Diabetes Mellitus.
Metabolites
January 2025
Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
This study evaluated metabolites and lipid composition in the calf muscles of Type 2 diabetes mellitus (T2DM) patients and age-matched healthy controls using multi-dimensional MR spectroscopic imaging. We also explored the association between muscle metabolites, lipids, and intra-abdominal fat in T2DM. Participants included 12 T2DM patients (60.
View Article and Find Full Text PDFSpatio-Temporal Analysis of Acute Myocardial Ischaemia Based on Entropy-Complexity Plane.
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December 2024
Grupo de Sistema Cardiovascular, Instituto de Ingeniería Biomédica (IIBM), Facultad de Ingeniería, Universidad de Buenos Aires, Buenos Aires C1063, Argentina.
Myocardial ischaemia is a decompensation of the oxygen supply and demand ratio, often caused by coronary atherosclerosis. During the initial stage of ischaemia, the electrical activity of the heart is disrupted, increasing the risk of malignant arrhythmias. The aim of this study is to understand the differential behaviour of the ECG during occlusion of both the left anterior descending (LAD) and right anterior coronary artery (RCA), respectively, using spatio-temporal quantifiers from information theory.
View Article and Find Full Text PDFRisk of Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Randomized Clinical Trials: A Systematic Review and Meta-Analysis.
Brain Sci
January 2025
Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA.
Background: Symptomatic intracranial hemorrhage (sICH) is the most dreaded complication after reperfusion therapy for acute ischemic stroke. We performed a meta-analysis of randomized controlled trials to estimate and compare risks of sICH after mechanical thrombectomy (MT) depending on the location of the large vessel occlusion, concomitant use of intravenous thrombolysis, timing of treatment, and core size.
Methods: Randomized controlled trials were included, following a comprehensive search of different databases from inception to 1 March 2024.
Bridging thrombolysis with tenecteplase versus endovascular thrombectomy alone for large-vessel anterior circulation stroke: a target trial emulation analysis.
J Neurol Neurosurg Psychiatry
January 2025
Department of Neurology and Stroke Center, University Hospital Basel and University of Basel, Basel, Switzerland.
Background: Whether bridging thrombolysis with tenecteplase is beneficial compared with thrombectomy alone in patients who had a stroke with large-vessel occlusion remains unclear.
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