Aim: The purpose of this study was to explore the process of living kidney donation as experienced by husbands of donors to aid nurses and all members of the health care team in promoting informed consent for those considering living donation and to promote the well being of spouses of living donors, donors and their families.
Background: The attitudes of husbands of living kidney donors may affect their decision to donate and satisfaction with recovery from donation surgery, thus it is critical to know how husbands of living kidney donors view kidney donation.
Methods: Eleven male spouses of living kidney donors were interviewed three months following their wife's donation. Grounded theory methodology was used to inaugurate a substantive theory that describes living kidney donation and its impact on the spousal relationship and family, as experienced by the husband of a donor.
Results: The result of the data analysis was a substantive theory pertaining strictly to the husbands' experiences as the spouse of the living kidney donor. The process commenced with scheduling of the living donation followed by the postoperative time frame, including bringing the donor wife home. The core variable, 'Fulfilling Your Vows', described attitudes, behaviours and actions that guided husbands in successfully and generously caring for their wives, their families, the recipients and themselves throughout the living kidney donation process and continuing 'to this day'.
Relevance To Clinical Practice: The substantive theory of 'Fulfilling Your Vows' will guide nurses and other transplant specialists in helping to improve fully informed consent of potential donors before surgery and in developing supportive strategies to maximize spouse, donor and family outcomes throughout the transplantation process.
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Sci Rep
December 2024
Department of Surgery, Division of Transplant Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Central body fat distribution affects kidney function. Abdominal fat measurements using computed tomography (CT) may prove superior in assessing body composition-related kidney risk in living kidney donors. This retrospective cohort study including 550 kidney donors aimed to determine the association between CT-measured abdominal fat areas and kidney function before and after donor nephrectomy.
View Article and Find Full Text PDFMed
December 2024
Nuffield Department of Surgical Sciences, University of Oxford, Oxford OX3 9DU, UK. Electronic address:
Background: Adoptive transfer of autologous regulatory T cells (Tregs) is a promising therapeutic strategy aimed at enabling immunosuppression minimization following kidney transplantation. In our phase 1 clinical trial of Treg therapy in living donor renal transplantation, the ONE Study (ClinicalTrials.gov: NCT02129881), we observed focal lymphocytic infiltrates in protocol kidney transplant biopsies that are not regularly seen in biopsies of patients receiving standard immunosuppression.
View Article and Find Full Text PDFCancer Treat Res Commun
December 2024
Dharmais National Cancer Center Hospital, Jakarta, Indonesia. Electronic address:
Background And Aim: Non-small cell lung cancer (NSCLC) is the most common lung cancer found in elderly patients. Aging and chronic inflammation are related to its pathogenesis. Functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio describe a chronic inflammation and correlate to the survival of older adults with advanced-stage (IIIB-IV) NSCLC.
View Article and Find Full Text PDFJMIR Public Health Surveill
December 2024
Evidence-Based Medicine Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen Street, Gucheng Street, Linhai, Zhejiang, 317000, China, 86 13666801279.
Background: Prisoner health is a major global concern, with prisoners often facing limited access to health care and enduring chronic diseases, infectious diseases, and poor mental health due to unsafe prison environments, unhygienic living conditions, and inadequate medical resources. In Taiwan, prison health is increasingly an issue, particularly concerning urinary diseases such as urinary tract infections. Limited access to health care and unsanitary conditions exacerbate these problems.
View Article and Find Full Text PDFCureus
November 2024
Department of Respiratory Medicine, Hippokration Hospital, Thessaloniki, GRC.
Introduction Physical inactivity is common in chronic kidney disease (CKD) patients; several patient- and disease-related factors are linked to a sedentary lifestyle, but social and environmental influences remain unexplored. This study evaluates the level of physical activity in patients with CKD and investigates the associations with caregivers' physical activity levels, characteristics of the residential environment, and objective measures of exercise capacity. Methods Eighty CKD patients (20 per CKD stage 2-4) were included; patients and their carers filled out the International Physical Activity Questionnaire (IPAQ), questionnaires about residential environment and past exercise habits.
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