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Walsucochins A and B with an unprecedented skeleton isolated from Walsura cochinchinensis. | LitMetric

Walsucochins A and B with an unprecedented skeleton isolated from Walsura cochinchinensis.

Org Lett

State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.

Published: February 2008

Walsucochins A (1) and B (2) with an unprecedented skeleton were isolated from Walsura cochinchinensis. Their structures including absolute configuration were elucidated by spectral methods. A biosynthetic pathway of 1 and 2 was postulated. Both 1 and 2 exhibited significant cell protecting activities against H2O2-induced PC12 cell damage.

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Source
http://dx.doi.org/10.1021/ol702831eDOI Listing

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