Purpose: To compare the preferential hyperacuity perimeter (Preview PHP; Carl Zeiss Meditec, Dublin, CA) with the original Amsler grid in the detection of choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD).
Methods: Patients were classified into groups, based on the severity of the age-related macular degeneration and underwent preferential hyperacuity perimeter and Amsler grid testing. High sensitivity and or high specificity of a method were defined as the observation of at least 80% of each one the parameters.
Results: Sixty-five patients (65 eyes) were analyzed statistically. The sensitivity of detection of choroidal neovascularization was 70% by the Amsler grid and 90% by the preferential hyperacuity perimeter and the specificity of the Amsler grid was 85.5% and that of the preferential hyperacuity perimeter 81.8%.
Conclusions: The preferential hyperacuity perimeter has greater sensitivity than the Amsler grid in the detection of choroidal neovascularization among patients over 50 years of age and is a promising method for monitoring patients with age-related macular degeneration. Although the original Amsler grid is less sensitive, it is a portable method, not expensive, accessible and presents reasonable sensitivity and high specificity in the diagnosis of choroidal neovascularization. Its use can be recommended for self-monitoring in patients with age-related macular degeneration as an alternative to preferential hyperacuity perimeter and when this method is not available.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1590/s0004-27492007000500009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tin contamination in sediments of Lake Zurich: source, spread, history and risk assessment.
Swiss J Geosci
December 2024
Department of Surface Waters Research and Management, Eawag, Überlandstrasse 133, Dübendorf, 8600 Switzerland.
Unlabelled: Industrial activities of a silk dyeing factory in Thalwil, on the shore of Lake Zurich, Switzerland, caused extreme Sn contamination of lake sediments. In this study, we determine the contamination source, spread, and age using a multiproxy approach. We used X-ray fluorescence spectroscopy (XRF) core scanning and further geochemical analyses to assess the contamination spreading and thickness in the sedimentary column.
View Article and Find Full Text PDFUse of Home Optical Coherence Tomography for Retinal Diseases.
Int Ophthalmol Clin
January 2025
Cullen Eye Institute, Baylor College of Medicine, Houston, TX.
Modern treatment protocols for retinal diseases involve frequent in-office monitoring with optical coherence tomography (OCT) and treatment with anti-vascular endothelial growth factor injections. Monthly injections may yield the greatest visual outcomes but are the most burdensome for patients and physicians, while as-needed injections may lead to undertreatment. Hybrid protocols, such as treat-and-extend (TREX) have been conceived to bridge this gap.
View Article and Find Full Text PDFSearch for violation in decays in proton-proton collisions at .
Eur Phys J C Part Fields
December 2024
Article Synopsis
- The CMS experiment conducted a search for charge-parity violation in decays using proton-proton collision data from 2018, analyzing around 10 billion events with b hadrons decaying into charm hadrons.
- The flavor of the neutral D meson was determined through the charge of pions in the reconstructed decays, and an asymmetry measurement in the decays was reported, taking into account various uncertainties.
- This research marks the first asymmetry measurement by the CMS in the charm sector and the first to use a fully hadronic final state in such analyses.
Antiproton annihilation at rest in thin solid targets and comparison with Monte Carlo simulations.
Eur Phys J A Hadron Nucl
November 2024
Stefan Meyer Institute for Subatomic Physics, Austrian Academy of Sciences, Vienna, Austria.
The mechanism of antiproton-nucleus annihilation at rest is not fully understood, despite substantial previous experimental and theoretical work. In this study we used slow extracted antiprotons from the ASACUSA apparatus at CERN to measure the charged particle multiplicities and their energy deposits from antiproton annihilations at rest on three different nuclei: carbon, molybdenum and gold. The results are compared with predictions from different models in the simulation tools Geant4 and FLUKA.
View Article and Find Full Text PDFObservation of the decay.
Eur Phys J C Part Fields
October 2024
Authors affiliated with an institute or an international laboratory covered by a cooperation agreement with CERN, Geneva, Switzerland.
Using proton-proton collision data corresponding to an integrated luminosity of collected by the CMS experiment at , the decay is observed for the first time, with a statistical significance exceeding 5 standard deviations. The relative branching fraction, with respect to the decay, is measured to be , where the first uncertainty is statistical, the second is systematic, and the third is related to the uncertainties in and .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!