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Molecular mechanisms behind the anti corona virus activity of small metal oxide nanoparticles.
Nanoscale
January 2025
Department of Molecular Science, BioCenter, Swedish University of Agricultural Sciences, Box 7015, 75007 Uppsala, Sweden.
The recent COVID-19 pandemic has set a strong quest for advanced understanding of possible tracks in abating and eliminating viral infections. In the view that several families of "pristine" small oxide nanoparticles (NPs) have demonstrated viricidal activity against SARS-CoV-2, we studied the effect of two NPs, with presumably different reactivity, on two viruses aiming to evaluate two "primary suspect" routes of their antiviral activity, either specific blocking of surface proteins or causing membrane disruption. The chosen NPs were non-photoactive 3.
View Article and Find Full Text PDFAn integrated theoretical study on natural alkaloids as SARS-CoV-2 main protease inhibitors: a step toward discovery of potential drug candidates with anti-COVID-19 activity.
RSC Adv
January 2025
Jiangsu Key Laboratory of Sericultural Biology and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology Zhenjiang 212100 China
: in the twenty-first century, the emergence of COVID-19 as a highly transmissible pandemic disease caused by SARS-CoV-2 posed a significant threat to humanity. : the disease spreads through small respiratory droplets, necessitating the use of various compounds for treatment, with alkaloids being recognized as particularly crucial owing to their diverse pharmaceutical properties. : in this study, a dataset comprising 100 natural alkaloids obtained from the literature was transformed into 2D chemical structures using Chem Draw 19.
View Article and Find Full Text PDFExploring Moiré Superlattices and Memristive Switching in Non-van der Waals Twisted Bilayer BiOSe.
ACS Appl Mater Interfaces
January 2025
Department of Physics, Indian Institute of Technology Guwahati, Guwahati 781039, India.
The discovery of moiré physics in two-dimensional (2D) materials has opened new avenues for exploring unique physical and chemical properties induced by intralayer/interlayer interactions. This study reports the experimental observation of moiré patterns in 2D bismuth oxyselenide (BiOSe) nanosheets grown through one-pot chemical reaction methods and a sonication-assisted layer separations technique. Our findings demonstrate that these moiré patterns result from the angular stacking of the nanosheets at various twist angles, leading to the formation of moiré superlattices (MSLs) with distinct periodicities.
View Article and Find Full Text PDFCamellia saponin modulates oleic acid/linoleic acid-induced lipogenesis in human sebocytes through lipophagy activation.
Int J Cosmet Sci
January 2025
School of Chemical and Material Engineering, Jiangnan University, Wuxi, China.
Background: Oily skin not only threatens people with aesthetic and hygienic discomfort but also confronts them with annoying skin problems. To explore new skin care ingredients from herbal or plant extracts and understand their underlying mechanism for sebum control would assist in the discovery of desirable sebosuppressive agents, though it is still a deserving and challenging task.
Aim: To explore the effect of Camellia saponin (CS) on modulating the lipogenesis of human sebocytes.
Self-assembly of malto-oligosaccharide-block-solanesol in aqueous solutions: Investigating morphology and sugar-based physiological compatibility.
Carbohydr Polym
March 2025
Faculty of Engineering, Hokkaido University, Sapporo 060-8628, Japan. Electronic address:
Starch-derived hydrophilic malto-oligosaccharides (Glc, where n = 1-7) conjugated to hydrophobic solanesol through click chemistry, i.e., Glc-b-Sol copolymers, have demonstrated significant promise in developing fully natural block co-oligomers for solid-state nanopatterning applications.
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