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Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells.
Eur Rev Med Pharmacol Sci
February 2024
Department of Otorhinolaryngology, ENT Specialist in Gazi Yaşargil Training and Research Hospital, Diyarbakir, Türkiye.
Objective: In the present study, we investigated the effects of 2-aminobenzothiazole application on human laryngeal carcinoma cells.
Materials And Methods: Human larynx epidermoid carcinoma (HEp-2) (ATCC® CCL-23™) cells were purchased from American Type Culture Collection (ATCC, USA). Human larynx epidermoid carcinoma HEp-2 cells were cultured in complete Dulbecco's Modified Eagle's Medium (DMEM) supplemented with fetal bovine serum (FBS) (10%) and penicillin/streptomycin (1%) in a CO2 (5%) incubator under standard cell culture conditions.
Effects of ceramide C2 application on human laryngeal carcinoma cells: a cell culture study.
Eur Rev Med Pharmacol Sci
October 2023
Department of Audiology, Istanbul Nişantaşı University, Health Services Vocational School, Istanbul, Turkey.
Objective: In the present study, we investigated the effects of Ceramide C2 application on human laryngeal carcinoma cells.
Materials And Methods: Human larynx epidermoid carcinoma HEp-2 (ATCC® CCL-23™) cells were purchased from the American Type Culture Collection (ATCC, USA). Human larynx epidermoid carcinoma HEp-2 cells were cultured in complete Dulbecco's Modified Eagle's Medium (DMEM) supplemented with fetal bovine serum (FBS) (10%) and penicillin/streptomycin (1%) in a CO2 (5%) incubator under standard cell culture conditions.
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine.
Proc Natl Acad Sci U S A
May 2018
Monell Chemical Senses Center, Philadelphia, PA 19104;
The hallmark features of type 2 mucosal immunity include intestinal tuft and goblet cell expansion initiated by tuft cell activation. How infectious agents that induce type 2 mucosal immunity are detected by tuft cells is unknown. Published microarray analysis suggested that succinate receptor 1 () is specifically expressed in tuft cells.
View Article and Find Full Text PDFAntibiotic-mediated bacteriome depletion in Apc mice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression.
Cancer Med
May 2018
Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
Recent epidemiological evidence suggests that exposure to antibiotics in early-to-middle adulthood is associated with an increased risk of colorectal adenoma. However, mechanistic studies in established preclinical cancer to examine these claims are extremely limited. Therefore, we investigated the effect of long-term exposure of an antibiotic cocktail composed of Vancomycin, Neomycin, and Streptomycin, on tumor development and progression in the Apc mouse, an established genetic model for familial adenomatous polyposis.
View Article and Find Full Text PDFThe Healing Effect of Conditioned Media and Bone Marrow-Derived Stem Cells in Laryngotracheal Stenosis: A Comparison in Experimental Dog Model.
World J Plast Surg
May 2017
Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Differences in causes, severities, areas of stenosis, and the association with swallowing and phonation of larynx and trachea can result into Laryngotracheal stenosis (LTS).This study evaluated the healing effect of bone marrow stem cells (BMSCs) in experimentally induced LTS dog model.
Methods: Seven dogs were enrolled.
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