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Antimicrobial susceptibility profiles among commensal Mannheimia haemolytica and Pasteurella multocida isolated from apparently healthy sheep processed in California: Results from a cross-sectional pilot study.
Prev Vet Med
December 2024
California Department of Food and Agriculture, Antimicrobial Use and Stewardship Program, 1220 N St, Sacramento, CA 95814, USA. Electronic address:
Article Synopsis
- Antimicrobial resistance (AMR) poses a significant challenge in treating bacterial infections in humans and animals, particularly in food-producing species like sheep, where data on bacterial susceptibility is limited.
- A study sampled the upper respiratory tracts of 620 sheep in California to analyze the susceptibility of the bacteria Mannheimia haemolytica and Pasteurella multocida, often linked to ovine respiratory disease (ORD).
- Results showed a 55.3% recovery rate of the target bacteria, with M. haemolytica exhibiting notable resistance to penicillin, while P. multocida was mostly susceptible, highlighting critical gaps in antimicrobial stewardship in veterinary practices.
Epidemiology and Healthcare of Juvenile and Late-Onset Acne: Claims Data Analysis.
Dermatol Ther (Heidelb)
November 2024
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany.
Article Synopsis
- * The study found significant differences in skin and non-skin-related comorbidities among those with acne, particularly in adults, with the majority receiving treatment from dermatologists and prescribed systemic therapies like anti-infectives and retinoids.
- * Results indicate that acne management in Germany is common but often does not adhere to established medical guidelines, highlighting a need for improved treatment protocols.
Polymers Enhance Chlortetracycline Hydrochloride Solubility.
Int J Mol Sci
October 2024
College of Veterinary Medicine, Gansu Agricultural University, Anning District, Lanzhou 730070, China.
Chlortetracycline hydrochloride (CTC) is a broad-spectrum tetracycline antibiotic with a wide range of antibacterial activities. Due to low solubility, poor stability, and low bioavailability, clinical preparation development is limited. We sought to improve these solubility and dissolution rates by preparing solid dispersions.
View Article and Find Full Text PDFIn vitro versus cryo-induced capacitation of bovine spermatozoa, part 3: Compositional and molecular changes to the plasma membrane.
Cryobiology
December 2024
Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76, Nitra, Slovakia.
Article Synopsis
- The study investigated how cryopreservation affects bovine sperm by measuring important proteins related to capacitation and apoptosis alongside membrane composition.
- Results showed that cryopreserved sperm (CRYO) had significantly lower sperm movement and higher DNA damage compared to both capacitated (CAP) and non-capacitated (CRTL) sperm.
- Notable changes in membrane composition included reduced levels of docosahexaenoic acid and cholesterol in CRYO sperm, along with down-regulated expression of capacitation-related proteins and altered levels of apoptosis-related proteins.
Chronic nonspecific cheilitis associated with tislelizumab treatment in a patient with a history of tongue squamous cell carcinoma: a case report.
BMC Oral Health
August 2024
Stomatological Hospital, School of Stomatology, Southern Medical University, 366# Southern Jiangnan Road, Guangzhou, Guangdong, 510280, China.
Article Synopsis
- Chronic nonspecific cheilitis is a condition causing persistent lip peeling and discomfort, particularly studied in a patient with a history of tongue squamous cell carcinoma treated with Tislelizumab.
- The patient experienced six months of lip peeling, and upon examination, was diagnosed with chronic nonspecific cheilitis and infectious angular cheilitis, leading to a personalized treatment plan involving oral hygiene and topical medications.
- The case highlights the need for tailored treatment in cancer patients receiving immunotherapy, showing that a comprehensive approach can improve symptoms and emphasize the importance of regular follow-ups for patient health.
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