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http://dx.doi.org/10.1136/oem.6.3.184 | DOI Listing |
Cureus
April 2024
Pulmonary and Critical Care, Ascension St. Vincent's Southside Hospital, Jacksonville, USA.
Pneumoconiosis is a form of interstitial lung disease (ILD) that commonly occurs secondary to occupational or environmental exposures. This is an emerging disease as there are many potential forms of pathologic insults. Further adding to the complication is that clinical symptomatology secondary to pneumoconiosis can have long latent periods, as repetitive exposure over years leads to long-standing inflammation and subsequent irreversible damage.
View Article and Find Full Text PDFToxics
October 2022
Department of Public Health and Pediatrics, University of Torino, 10126 Turin, Italy.
There is contrasting data on the association between talc exposure and lung and pleural cancer. Given the potential importance of this aspect, we performed a systematic review and meta-analysis to investigate the association between working in the talc extractive industry and mortality from malignant and non-malignant respiratory diseases. We followed PRISMA guidelines to systematically search for pertinent articles in three relevant electronic databases: Pubmed, Scopus, and WebOfScience, from their inception to 30 November 2021.
View Article and Find Full Text PDFTurk Thorac J
November 2022
Department of Pulmonary Medicine, Dokuz Eylül University, İzmir, Turkey.
Pneumoconiosis is a lung disease that develops as a result of a tissue reaction that occurs with the accumulation of inorganic particles. Pathoclinical features may vary depending on the type of inhaled particle. Today, fibrotic and nonfibrotic tissue reactions are well defined in some substances.
View Article and Find Full Text PDFFront Public Health
August 2022
MY EpiConsulting, Düsseldorf, Germany.
Inhaled particles that are poorly soluble or insoluble and of low toxicity ("poorly soluble low toxicity" or "PSLT" particles), can accumulate in the lung and at lung overload levels induce lung cancers in rats. The question of whether PSLT particles increase lung cancer risk in humans is complicated by large differences between rats and humans and the relatively large particle doses administered in animal studies even when compared with heavy human occupational exposures. We review the findings of epidemiological studies on occupational exposure to each of three different PSLT particles (carbon black, talc and taconite).
View Article and Find Full Text PDFRespir Med Case Rep
July 2021
University of Maryland Medical Center & Baltimore VA Medical Center, Baltimore, MD, USA.
Pulmonary talcosis is a rare pneumoconiosis that is difficult to diagnose and may progress to debilitating lung disease. Four types of talcosis are described in literature: talc-silicosis and talc-asbestosis secondary to inhalation in industry workers and talc-emboli in intravenous drug users that self-inject talc-containing oral tablets. Although found in common household products, talc is overlooked as a cause of pneumoconiosis.
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