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Relationship between the root processing method and quality of herbal medicine of Rauvolfia serpentina cultivated in Japan.
Fitoterapia
October 2024
Department of Medicinal Plant, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan. Electronic address:
Article Synopsis
- Rauvolfia serpentina roots are used in Southeast Asian herbal medicine for various ailments including snake bites, fever, hypertension, and dysentery.
- The study evaluated the content of key active ingredients (reserpine, ajmaline, and ajmalicine) in the roots processed using different methods on plants cultivated in Japan.
- Results showed that a 30-minute drum mixer washing method is efficient for root processing, and active ingredient content is consistent across different root sizes, indicating uniform quality of the crude drug.
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School of Pharmacy, University of Camerino, Camerino, Italy.
Hypertension is a serious concern as it is one of the causes of kideny failure and pulmonary fibrosis. An important therapeutic strategy for treating chronic hypertension is to inhibit the angiotensin converting enzyme (ACE). ACE inhibition reduces kidney damage, pulmonary artery pressure, and high blood pressure.
View Article and Find Full Text PDFBiotechnological interventions and indole alkaloid production in Rauvolfia serpentina.
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Department of Biotechnology, Faculty of Technology and Sciences, Lovely Professional University, Phagwara, Punjab, India.
Rauvolfia serpentina (L). Benth. ex Kurz.
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Nanotechnology and Nanomedicine Lab-6(IIRC), Department of Biosciences, Integral University, Lucknow 226026, India.
(), belonging to the family Apocynaceae, is a renowned medicinal herb for its different pharmacological activities such as antibacterial, antifungal, anti-inflammatory, and antiproliferative characteristics. This study has done a comparative assessment of the antibacterial, antioxidant, and anti-cancer activity of aqueous leaf extract (RSALE) with encapsulated gold nanoparticles (R-AuNPs). The R-AuNPs are prepared so that they are significant in size, monodispersed, and extremely stable.
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Bioscreening Unit, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, Thailand.
Objectives: Alzheimer's disease (AD) is a degenerative brain disease characterized by confusion, behavior changes, decline in memory and cognitive skills. One of the strategies in the treatment of AD is to use acetylcholinesterase (AChE) inhibitors. The current study aims to determine the AChE inhibitory activities of the extract and fractions of the root of .
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