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Epidemiological Characteristics of Mumps Cases in the Kingdom of Bahrain From 2012 to 2022.
Cureus
December 2024
Department of Family and Community Medicine, Arabian Gulf University, Manama, BHR.
Introduction: Mumps is a vaccine-preventable disease caused by the paramyxovirus affecting the salivary gland and may be complicated by orchitis, oophoritis, and encephalitis. This study aims to describe the epidemiology, clinical presentation, and transmission of mumps cases in the Kingdom of Bahrain between 2012 and 2022.
Methodology: A retrospective cross-sectional study was conducted using national surveillance data of confirmed mumps cases, including all age groups and both Bahraini and non-Bahraini nationals, from January 2012 to December 2022.
Unsupported walking with only half of the brain due to severe porencephaly.
J Family Med Prim Care
December 2024
Neurology Neurophysiology Center, Vienna, Austria.
A patient with a history of Asian flu, mumps meningo-encephalitis, and skull-base fracture and severe porencephaly who was able to walk without assistance, has not been reported. The patient is a 65 year-old male with a history of Asian flu at 6 months of age, Mumps meningoencephalitis at 6 years of age, structural epilepsy since 15 years of age, traumatic brain injury with skull-base fracture at 51 years of age, arterial hypertension, diabetes, hyperlipidemia, previous alcoholism, and polyneuropathy. He presented with only mild right-sided spastic hemiparesis, dysarthria, decreased tendon reflexes in the lower limbs, spastic-ataxic gait, but he was able to walk unassisted.
View Article and Find Full Text PDFBroad Analysis of Serum and Intrathecal Antimicrobial Antibodies in Multiple Sclerosis Underscores Unique Role of Epstein-Barr Virus.
Neurol Neuroimmunol Neuroinflamm
January 2025
From the Department of Neurology (F.P., C.O., P.S., M.N., K.R.), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin; Institute for Experimental Immunology (D.W., T.L., K.S., E.G.-G.), affiliated with EUROIMMUN Medizinische Labordiagnostika AG, Luebeck; and Molecular Neuroimmunology Group (B.W., S.J.), Department of Neurology, University of Heidelberg, Germany.
Article Synopsis
- - The study investigates the relationship between the Epstein-Barr virus (EBV) and multiple sclerosis (MS) by analyzing the presence of antibodies against EBV and other common microbes in patients with MS, revealing a universal EBV seroprevalence among participants.
- - A total of 50 MS patients were tested for antibodies in their cerebrospinal fluid (CSF) and serum, finding that while all patients were EBV positive, the production of specific antibodies in the CSF was significantly lower for EBV compared to other viruses like measles and VZV.
- - The results indicate that even though almost all MS patients have been exposed to EBV, the actual production of antibodies against EBV in the central
Exposure to Pollutants and Vaccines' Effectiveness: A Systematic Review.
Vaccines (Basel)
November 2024
Department of Medical, Movement and Wellbeing Sciences, University of Naples "Parthenope", 80133 Naples, Italy.
Many human activities release harmful substances, contaminating the air, water, and soil. Since exposure to environmental pollutants is currently unavoidable, it is important to verify how these compounds may influence individual immune responses to vaccines. This review was conducted in accordance with the PRISMA statement.
View Article and Find Full Text PDFGlobal and Regional Burden of Vaccine-Associated Erythema Multiforme and Their Related Vaccines, 1967-2023: An In-Depth Analysis of the World Health Organization Pharmacovigilance Database.
Med Princ Pract
October 2024
Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- This study investigates the understudied issue of vaccine-associated erythema multiforme (EM) and its link to specific vaccines, aiming to improve global vaccine safety evaluations.
- By analyzing over 131 million reports from the WHO database (1967-2023), the research identified 6,355 cases of vaccine-associated EM, with notable spikes in incidence around 2010 and 2020, especially linked to measles, mumps, rubella, and hepatitis vaccines.
- Findings indicate a higher occurrence of vaccine-associated EM in younger males, with a very low fatality rate (0.04%), stressing the importance of monitoring and refining vaccination strategies to reduce adverse effects.
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