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Background infections pose a significant challenge in low- and middle-income countries, contributing to child mortality. is linked to acute gastrointestinal illness and severe long-term consequences, including environmental enteric dysfunction (EED) and stunting. In 2018, our cross-sectional study in Ethiopia detected in 88% of stools from children aged 12-15 months, with an average of 11 species per stool using meta-total RNA sequencing.
View Article and Find Full Text PDFSerological, phenotypic and molecular characterization of brucellosis in small ruminants in northern Algeria.
Front Microbiol
January 2025
Friedrich-Loeffler-Institut, Institute of Bacterial Infections and Zoonoses, Jena, Germany.
Brucellosis is considered a common bacterial zoonotic disease of high prevalence in countries of the Middle East and the Mediterranean region with economic and public health impact. The present study aimed to investigate the current situation of brucellosis in small ruminants reared in Médéa and Sidi Bel-Abbès provinces, north Algeria. To achieve this objective, 96 sera (77 sheep and 19 goat) and 57 milk (42 sheep and 15 goat) samples were collected from suspected infected animals and serologically analyzed by using ELISA.
View Article and Find Full Text PDFRuminal microbial responses to Moringa oleifera feed in lactating goats (Capra hircus): A metagenomic exploration.
N Biotechnol
January 2025
Gujarat Biotechnology Research Centre, Gandhinagar, 382011, Gujarat, India. Electronic address:
The purpose of the current study was to explore the effects of Moringa oleifera feed on the taxonomy and function of the rumen microbial community, and further to evaluate its impact on milk yield and body weight in lactating goats. Nineteen goats were divided into moringa leaf diet (ML; n=10) and masoor straw (MS; n=9) groups. For each group fortnight milk yield and body weight was recorded.
View Article and Find Full Text PDFBioactive peptides with antioxidant and ACE inhibitory properties in goat milk protein hydrolysates: Peptidomics and molecular docking study.
Int J Biol Macromol
January 2025
College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, Shaanxi, China. Electronic address:
This study identified the amino acid sequences of peptides generated from the enzymatic hydrolysis of goat milk proteins from two different sources and annotated their functional activities. Peptidomics and molecular docking approaches were used to investigate the antioxidant and ACE inhibitory properties of the unique peptides, revealing the molecular mechanisms underlying their bioactivity. In vitro experiments showed that the IC50 values for ACE inhibition of the four peptides (LSMTDTR, QEALELIR, NIPVGILR, and QAQNVQHY) were 2.
View Article and Find Full Text PDFGenomic Landscape and Prediction of Udder Traits in Saanen Dairy Goats.
Animals (Basel)
January 2025
Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Goats are essential to the dairy industry in Shaanxi, China, with udder traits playing a critical role in determining milk production and economic value for breeding programs. However, the direct measurement of these traits in dairy goats is challenging and resource-intensive. This study leveraged genotyping imputation to explore the genetic parameters and architecture of udder traits and assess the efficiency of genomic prediction methods.
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