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The only macular heredodegeneration which can be diagnosed by electrophysiological tests is the dominant vitelliform degeneration of the macula, the ERG being normal and the EOG very pathologic. In the pre- or subclinical or polymorphous atrophic stages it is even the only possibility of making the diagnosis. Autosomal dominant pigmentary retinopathy can rather often be differentiated from autosomal or sex-linked recessive pigmentary retinopathy by the fact that there is still an ERG response and more particularly a cone response and that its progressive deterioration is observed, while in autosomal or sex-linked recessive pigmentary retinopathy the ERG is mostly extinguished.
View Article and Find Full Text PDF[Early macular heredo-degeneration; Best's disease and vitelliform disk].
Bull Soc Belge Ophtalmol
June 1968
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