A series of aziridinederivatives of N,N'-bis-butanoylalkylenodiamines (Scheme 1, 1-4) and aziridinederivatives of substituted succinic acid (Scheme 2, 16-19) was obtained. Pharmacological analysis revealed that these compounds were immunotropic, of marked suppressive effect (PFC, RFC, circulating immunoglobulins). Outstanding in this group was phenyloimide of succinic acid (prep. 16) which reduced PFC and RFC number but increased the level of circulating IgG.
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