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Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS-A multicentre case-control study.
Sci Rep
January 2025
Clinical Infection, Microbiology & Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little is known about the relative outcomes in patients with COVID-19 neurological or psychiatric complications. We conducted a UK multicentre case-control study of patients hospitalised with COVID-19 (controls) and those who developed COVID-19 associated acute neurological or psychiatric complications (cases).
View Article and Find Full Text PDFFactors Associated with Persisting Post-Concussion Symptoms Among Collegiate Athletes and Military Cadets: Findings from the NCAA-DoD CARE Consortium.
Sports Med
January 2025
IU School of Optometry and Program in Neuroscience, Indiana University, Bloomington, IN, USA.
Background: Persisting post-concussion symptoms (PPCS) is a condition characterized by prolonged recovery from a mild traumatic brain injury (mTBI) and compromised quality of life. Previous literature, on the basis of small sample sizes, concludes that there are several risk factors for the development of PPCS.
Objective: We seek to identify protective and risk factors for developing slow recovery or persisting post-concussion symptoms (PPCS) by analyzing medical history, contact sport level, setting, and the Sport Concussion Assessment Tool (SCAT) and Brief Symptom Inventory (BSI-18) assessments at baseline and post-injury.
THE SCALE INSECTS OF IRAN (HEMIPTERA: COCCOMORPHA) PART 3 THE SOFT SCALES (COCCIDAE) AND OTHER FAMILIES.
Zootaxa
November 2024
Science: Research; Natural History Museum; Cromwell Road; London SW7 5BD; U.K..
The present work is the third and final part in a series of monographs on the Iranian scale insect fauna (Hemiptera: Coccomorpha) by the same authors: Part 1, the armoured scales (Diaspididae), was published in 2021, and Part 2, the mealybugs (Pseudococcidae and Rhizoecidae) and Putoidae, was published in 2022. Here we cover ten families: Asterolecaniidae, Cerococcidae, Coccidae, Cryptococcidae, Eriococcidae, Kermesidae, Margarodidae, Monophlebidae, Ortheziidae and Phoenicococcidae, bringing the total number of scale insect families recorded in Iran to 14. A key is provided to separate all 14 families.
View Article and Find Full Text PDFPlausible Action of N-(3,4-Dimethoxy-Phenyl)-6,7-Dimethoxyquinazoline-4-Amine (TKM01) as an Armor Against Alzheimer's Disease: In Silico and In Vivo Insights.
J Biochem Mol Toxicol
December 2024
School of Life Sciences, B.S. Abdur Rahman Crescent Institute of Science and Technology, Chennai, India.
Alzheimer's disease (AD) affects millions of people and has limited treatment options, thus making it a global health concern. Amyloid β (Aβ), a disrupted cholinergic system with high acetylcholinesterase (AChE), oxidative stress (OS), reduced antioxidants, and neuroinflammation are key factors influencing AD progression. Prior research has shown that AChE can interact with Aβ and increase its accumulation and neurotoxicity, so targeting AChEs and Aβ could be a potential therapeutic approach for AD treatment.
View Article and Find Full Text PDFArmored brain as a late complication of CSF overshunting: A rare case report.
Radiol Case Rep
January 2025
Adama Comprehensive Specialized Hospital Medical College, Department of Radiology, Adama, Ethiopia.
We hereby present a case of an 18-year-old patient who, following initial cerebrospinal fluid overshunting to relieve a congenital hydrocephalus for Dandy-Walker malformation, developed chronic calcified subdural hematoma or an armored brain as a late complication. Chronic calcified subdural hematoma or armored brain is generally rare, and it is even rarer after overshunting. In this report, we present a rare case of bilateral chronic subdural hematoma, also known as "armored brain", 18 years after a ventriculoperitoneal shunt was placed during infancy.
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