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Clinical Manifestations.
Alzheimers Dement
December 2024
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: Hearing loss is highly prevalent and can have significant consequences for older adults aging with cognitive impairment. However, few older adults use hearing aids and disparities in care exist by race, ethnicity, and socioeconomic position. To understand the intersection of hearing loss and cognitive impairment with the ultimate goal of developing an affordable, accessible hearing care intervention responsive to the needs of end-users, a series of semi-structured interviews was conducted.
View Article and Find Full Text PDFExpert Consensus on an Exercise Prescription Framework for Older People Living With HIV in a South African Setting-A Delphi Study.
J Assoc Nurses AIDS Care
January 2025
Levin Chetty, PhD, MMSHSC, SPTSHB, B-SPS, is an Academic Researcher, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, South Africa.
Well-established, regular exercise interventions for older people living with HIV (OPLWH) are beneficial. However, the fundamental principles of exercise prescription for this population have not been sufficiently explored. An expert panel of health care professionals engaged in a modified Delphi technique to explore their perceptions of, and gain their consensus on, an exercise prescription framework for OPLWH in a resource-poor South African setting.
View Article and Find Full Text PDFViruses and psychiatric disorders: We have not crossed the borderline from hypothesis to proof yet (Review).
Mol Med Rep
March 2025
2nd Department of Psychiatry, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.
Most psychiatric disorders are heterogeneous and are attributed to the synergistic action of a multitude of factors. It is generally accepted that psychiatric disorders are the outcome of interactions between genetic predisposition and environmental perturbations, which involve psychosocial stress, or alterations in the physiological state of the organism. A number of hypotheses have been presented on such environmental influences that may include direct insults such as injury, malnutrition and hostile living conditions, or indirect sequelae following infection from viruses such as influenza, arboviruses, enteroviruses and several herpesviruses, or the differential expression of human endogenous retroviruses.
View Article and Find Full Text PDFIntroduction: Antiretroviral therapy (ART) initiation, regardless of CD4 count, has been recommended in Thailand since 2014, with same-day initiation recommended since 2021. We assessed HIV treatment outcomes among Thai people living with HIV (PLHIV) by the time from HIV diagnosis to ART initiation under the Universal Health Coverage (UHC) programme and identified factors associated with virological failure (VF).
Methods: PLHIV aged ≥15 years initiating ART between 2014 and 2022 were included from the UHC database.
Patterns of liver fibrosis evolution in Chinese HIV/HBV co-infected adults following 5-year antiretroviral treatment: a longitudinal study using non-invasive APRI and Fib-4 scores.
Virol Sin
December 2024
School of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, 510080, China; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China. Electronic address:
The long-term effects of combined antiretroviral therapy (ART) on liver fibrosis patterns in adults living with HIV and chronic hepatitis B virus (HBV) are not well understood. Therefore, this study aimed to investigate the trajectories of liver fibrosis and identify the associations of baseline variables with different patterns of liver fibrosis evolution. A total of 333 individuals with HIV/HBV co-infection and undergoing long-term ART were enrolled in this study.
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