Effect of gold nanoparticle on the microscopic morphology of white blood cell.

Cytopathology

Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Published: April 2009

Background: In medicine, there is limited knowledge on the toxicity of nanoparticles. In medicine, there has been limited knowledge on the effect of nanoparticles on the white blood cell.

Objective: To evaluate the effect of gold nanoparticle on the microscopic morphology of white blood cell.

Setting: Chulalongkorn Univesity, Bangkok, Thailand.

Method: This study was performed as an experimental study. Mixture of gold nanoparticle solution and blood sample was prepared and analysed.

Result: This work revealed that after mixing the blood sample with gold nanoparticle solution, accumulation of gold nanoparticle in the white blood cell was observed.

Conclusion: The effect of gold nanoparticle on the white blood cell can be detected and this knowledge can be used in cytotoxic drug treatment.

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Source
http://dx.doi.org/10.1111/j.1365-2303.2007.00532.xDOI Listing

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