The preparation of a variety of optically pure peptides containing an N-1H,1H-perfluoroalkyl label on a selected backbone amide bond is now possible.
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Effect of different intensity aerobic exercise on remodeling immune microenvironment of adipose tissue in obesity mouse.
Am J Physiol Regul Integr Comp Physiol
January 2025
College of Sport and Health, Shandong Sport University, Jinan, Shandong, 250102, China.
Obesity can change the immune microenvironment of adipose tissue and induce inflammation. This study is dedicated to exploring the internal mechanism by which different intensities of exercise reprogram the immune microenvironment of epididymal adipose tissue in nutritionally obese mice. C57BL/6J male obese mouse models were constructed by high-fat diet, which were respectively obese control group (OC), moderate intensity continuous exercise group (HF-M), high intensity continuous exercise group (HF-H) and high intensity intermittent exercise group (HF-T).
View Article and Find Full Text PDFExploring PrEP Motivation as a Modifiable Target for HIV Prevention Uptake for Cisgender Women in Atlanta, Georgia.
J Acquir Immune Defic Syndr
January 2025
Emory University Rollins School of Public Health, Department of Behavioral, Social, and Health Education Sciences.
Background: Pre-exposure prophylaxis for HIV prevention (PrEP) prescriptions in the U.S. have increased, yet only 15% of individuals assigned female at birth who could benefit from PrEP had received prescriptions as of 2022, with marked racial disparities.
View Article and Find Full Text PDFconstructed polymer-layer-modified solid electrolyte enables high-performance all-solid-state batteries.
Chem Commun (Camb)
January 2025
School of Materials Science and Engineering, Zhejiang University, 866 Yuhangtang Rd, Hangzhou 310058, China.
Side reactions between electrolyte and anode hinder the application of solid-state batteries. Here, a polymer-containing composite solid-state electrolyte (LiPSCl@PCSSE) was obtained through polymerization on LiPSCl. The novel electrolyte was indicated to inhibit side reactions, and the pouch cell showed excellent performance, demonstrating its practical application owing to the employment of LiPSCl@PCSSE.
View Article and Find Full Text PDFSubjective views of couple's joint aging: Development of a new scale.
J Fam Psychol
January 2025
Department of Social and Health Sciences, Bar-Ilan University.
Subjective views of aging (VoA) play a crucial role in shaping individuals' physical, mental, and overall well-being. While past research has primarily focused on individual perspectives, recent literature suggests the development of VoA within interpersonal relationships. This study introduces a new scale, the Views of Couple Joint Aging (VoCJA), examining VoA related to the aging process within couple partnerships.
View Article and Find Full Text PDFDesign and Generation of TEMPO Reagents for Sequential Labeling and Manipulation of Vertebrate Cell Lineages.
Methods Mol Biol
January 2025
Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
During development, cells undergo a sequence of specification events to form functional tissues and organs. To investigate complex tissue development, it is crucial to visualize how cell lineages emerge and to be able to manipulate regulatory factors with temporal control. We recently developed TEMPO (Temporal Encoding and Manipulation in a Predefined Order), a genetic tool to label with different colors and genetically manipulate consecutive cell generations in vertebrates.
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