A 36-year-old man with a remote history of Hodgkin lymphoma and a recent history of non-Hodgkin lymphoma (NHL) developed tonic pupils and absent deep tendon reflexes in the lower extremities. One year later, pupils were normal except for slight iris segmental contraction to light. Over the next 2 years, the patient remained asymptomatic, and pupils remained unchanged. The NHL went into remission, and no other neurologic manifestations appeared. This is the first report of reversible tonic pupils. They may have a pathogenesis different from that typically seen in irreversible tonic pupils.
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http://dx.doi.org/10.1097/WNO.0b013e31815b9a3a | DOI Listing |
Psychon Bull Rev
January 2025
Department of Psychology, McGill University, 2001 Av. McGill College, Montréal, QC, H3A 1G1, Canada.
A growing body of evidence across psychology suggests that (cognitive) effort exertion increases in proximity to a goal state. For instance, previous work has shown that participants respond more quickly, but not less accurately, when they near a goal-as indicated by a filling progress bar. Yet it remains unclear when over the course of a cognitively demanding task do people monitor progress information: Do they continuously monitor their goal progress over the course of a task, or attend more frequently to it as they near their goal? To answer this question, we used eye-tracking to examine trial-by-trial changes in progress monitoring as participants completed blocks of an attentionally demanding oddball task.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Neurosurgery, Baylor College of Medicine, Houston, USA.
Alteration of responses to salient stimuli occurs in a wide range of brain disorders and may be rooted in pathophysiological brain state dynamics. Specifically, tonic and phasic modes of activity in the reticular activating system (RAS) influence, and are influenced by, salient stimuli, respectively. The RAS influences the spectral characteristics of activity in the neocortex, shifting the balance between low- and high-frequency fluctuations.
View Article and Find Full Text PDFPsychophysiology
December 2024
Department of Experimental Psychology, Ghent University, Ghent, Belgium.
Response inhibition is key to flexible behavior. Importantly, performance in any task, including response inhibition tasks, fluctuates on a moment-to-moment basis. Using pupillometry, we investigated the relationship between these behavioral fluctuations in response inhibition and naturally occurring fluctuations of norepinephrine (NE) levels in the brain before a given trial has even started.
View Article and Find Full Text PDFCase Rep Oncol
December 2024
Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Floridablanca, Colombia.
Introduction: Chondrosarcomas are cartilaginous tumors primarily known for metastasizing to the lungs and bones. Their spread to the central nervous system is infrequent.
Case Presentation: We present the case of a 32-year-old woman with a history of pelvic/sacral grade III chondrosarcoma (L4-S2; T3N0MX; Ki67; 30%), who underwent surgical resection and radiotherapy.
Conscious Cogn
November 2024
Mind, Brain and Behavior Research Center (CIMCYC), University of Granada, Granada, Spain; Department of Experimental Psychology, University of Granada, Granada, Spain.
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