Background: Early identification of patients at risk for delayed recovery after an injury is important to effectively target rehabilitation. This study presents a new instrument, the Prediction of Prolonged Self-Perceived Recovery After Musculoskeletal Injuries questionnaire (PPS), for prediction of self-perceived nonrecovery after musculoskeletal injuries.
Methods: On the basis of a historic cohort (model building set, n = 557), we constructed the PPS consisting of two demographic variables (educational level and working status), a crude injury classification, and patient-rated physical and mental complaints during the acute phase of the injury. We evaluated the PPS's ability to predict self-perceived nonrecovery at 6 months in a new group of patients with minor musculoskeletal traffic-related injuries (validation set, n = 279).
Results: Our findings demonstrate that the PPS foresees an unfavorable course with a greater accuracy than prediction based exclusively on information about the injury. The overall percentage of correct predictions in the model building set was 77%. The overall percentage of correct predictions in the validation set was 67%. The sensitivity and specificity in relation to nonrecovery at 6 months was 55% and 73%, respectively.
Conclusions: This is the first prospective clinical study in which an instrument is used for prediction purpose. On the basis of our results, we think that the PPS, even if not fully developed, can be used by clinicians as a tool for early identification of patients at risk for delayed recovery after trauma. A nonnegligible proportion of the patients who would benefit from additional rehabilitation are missed by the instrument in its present form. Further research is needed to verify our results.
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http://dx.doi.org/10.1097/01.ta.0000240174.56751.3e | DOI Listing |
Neuroimage
January 2025
Department of Psychiatry, University of Florida, Gainesville, FL-32610; McKnight Brain Institute, University of Florida, Gainesville, FL-32610. Electronic address:
Sepsis is a state of systemic immune dysregulation and organ failure that is frequently associated with severe brain disability. Epidemiological studies have indicated that younger females have better prognosis and clinical outcomes relative to males, though the sex-dependent response of the brain to sepsis during post-sepsis recovery remains largely uncharacterized. Using a modified polymicrobial intra-abdominal murine model of surgical sepsis, we characterized the acute effects of intra-abdominal sepsis on peripheral inflammation, brain inflammation and brain functional connectivity in young adult mice of both sexes.
View Article and Find Full Text PDFIntroduction And Importance: Neglected posterior hip dislocations in adults are rare, particularly when untreated for years. In developing nations, patients often rely on traditional bone setters, leading to delayed diagnosis and increased complications. Adult hip dislocations carry a higher risk of avascular necrosis and require complex treatments.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Harish-Chandra Research Institute, A CI of Homi Bhabha National Institute, Chhatnag Road, Jhusi, Allahabad 211019, India.
Pump-probe response of the spin-orbit coupled Mott insulator Sr_{2}IrO_{4} reveals a rapid creation of low-energy optical weight and suppression of three-dimensional magnetic order on laser pumping. Postpump there is a quick reduction of the optical weight but a very slow recovery of the magnetic order-the difference is attributed to weak interlayer exchange in Sr_{2}IrO_{4} delaying the recovery of three-dimensional magnetic order. We suggest that the effect has a very different and more fundamental origin.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Background: Visual Cognitive Assessment Test(VCAT) is a visual-based cognitive evaluation tool which can be administered to multilingual populations without translation. VCAT has shown to be effective in differentiating mild cognitive impairment(MCI) from cognitively normal and useful for diagnosing MCI and mild AD(Kandiah et al., 2016).
View Article and Find Full Text PDFClin Spine Surg
January 2025
Chair and Department of Palliative Medicine, University of Medical Sciences, Poznań, Poland.
Study Design: This was a narrative review.
Objective: The objective of this review was to summarize the current evidence and knowledge gaps regarding anesthesia and pain management for scoliosis surgery, including multimodal analgesia, and identify the best anesthetic approach to scoliosis surgery that ensures patient safety and pain relief even in the postoperative period, with minimal influence on SSEP monitoring.
Summary Of Background Data: Spinal surgeries and fusions for scoliosis are associated with high pain levels.
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