Procedures were developed to produce infectious Epstein-Barr virus in large glass fermentors with limited mechanical agitation by using an intermittent culture collection system. The system appears quite suitable for use in fermentation vessels of 50 liters or larger.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC169868PMC
http://dx.doi.org/10.1128/aem.31.6.995-998.1976DOI Listing

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