We report on the ultrahigh long-term dimensional stability of a crystalline cryogenic optical resonator (CORE) cooled to liquid-helium temperature. The frequency of a Nd:YAG laser stabilized to a CORE was compared over long times with an independent laser system, a frequency-doubled Nd:YAG laser stabilized to a hyperfine line of molecular iodine at 532 nm. Over a 6-month period the drift was less than 3 kHz. The dimensional stability of the CORE is thus more than 2 orders of magnitude higher than that of the best ultralow-expansion glass ceramic cavities at room temperature.
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http://dx.doi.org/10.1364/ol.23.001031 | DOI Listing |
Spine Deform
January 2025
Department of Orthopedic Surgery, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Purpose: Scoliosis is a complex multi-dimensional deformity of the spine that is common in children and adults. Of the various treatments for scoliosis, one is posterior spinal fusion with instrumentation. The rods typically used are composed of titanium or cobalt-chrome.
View Article and Find Full Text PDFJ Theor Biol
January 2025
Center for Mathematical Biosciences, School of Mathematics and Statistics, Northeast Normal University, Changchun, 130024, PR China. Electronic address:
Coral reef ecosystem is a crucial component of marine ecosystems and is undergoing severe degradation due to the combined dural impact of environmental changes and human activities. Soundscape technology is an innovative coral reef restoration approach that attracts fish to degraded reefs. Inspired by such technique, a five-dimensional mathematical dynamical model incorporating the asymmetric dispersal of parrotfish is formulated to characterize the dynamic interaction among macroalgae, coral, algal turf, and parrotfish in coral reef ecosystem.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
School of Food Science and Technology, Jiangnan University, Wuxi, PR China.
This study investigates camel milk protein structural dynamics during digestion using Fourier Transform Infrared (FTIR) spectroscopy and Two-Dimensional Infrared (2D-IR) homo-correlation and hetero-correlation analysis. The synchronous 2DIR homo-correlation map reveals that NH bending and C-N stretching vibrations (amide II) are sensitive to digestion, indicating significant impacts on secondary structures. The asynchronous 2DIR homo-correlation indicates a stepwise process, where initial disruptions in NH interactions precede changes in CO stretching vibrations (amide I), highlighting the sequence of structural alterations during protein unfolding and degradation.
View Article and Find Full Text PDFJ Vis Exp
January 2025
Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Henry and Allison McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School;
A method to quantitate the stabilization of Mitochondria-Associated endoplasmic reticulum Membranes (MAMs) in a 3-dimensional (3D) neural model of Alzheimer's disease (AD) is presented here. To begin, fresh human neuro progenitor ReN cells expressing β-amyloid precursor protein (APP) containing familial Alzheimer's disease (FAD) or naïve ReN cells are grown in thin (1:100) Matrigel-coated tissue culture plates. After the cells reach confluency, these are electroporated with expression plasmids encoding red fluorescence protein (RFP)-conjugated mitochondria-binding sequence of AKAP1(34-63) (Mito-RFP) that detects mitochondria or constitutive MAM stabilizers MAM 1X or MAM 9X that stabilize tight (6 nm ± 1 nm gap width) or loose (24 nm ± 3 nm gap width) MAMs, respectively.
View Article and Find Full Text PDFJ Vis Exp
January 2025
School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine;
The therapeutic effectiveness of acupuncture relies on both safety and stability, making these factors essential in acupuncture manipulation research. However, manual manipulation introduces unavoidable inaccuracies, which can impact the reliability of research findings. To address this challenge, a unique lifting and thrusting manipulation control cannula was designed in this study, offering flexible adjustment of movement amplitude.
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