This is the last Informatics Education column under the current editors. The outgoing editors identify six key themes that reflect the changes in informatics education over their seven-year tenure. The themes are picked from the 29 previous columns published under their editorship. The first and key theme is technology, and this one theme is the basis for the other five. The incoming editors project what they expect to see as key themes for future columns. Together, this column looks at the past, present, and future state of informatics education in the United States.
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http://dx.doi.org/10.1300/J115v26n04_08 | DOI Listing |
Behav Res Methods
January 2025
Institute of Developmental Psychology, Faculty of Psychology, Beijing Normal University, No.19 Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Over the past few decades, Swahili-English and Lithuanian-English word pair databases have been extensively utilized in research on learning and memory. However, these normative databases are specifically designed for generating study stimuli in learning and memory research involving native (or fluent) English speakers. Consequently, they are not suitable for investigations that encompass populations whose first language is not English, such as Chinese individuals.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of California, San Francisco, Weill Institute for Neurosciences, San Francisco, CA, USA.
Background: Alzheimer's disease (AD) and other dementia risk may be influenced by the immune function and associated with several white blood cell type counts. In cognitively normal Black, Hispanic, and non-Hispanic white older adults we related three white blood cell types previously associated with AD risk to tau positron emission tomography (PET) values in the medial temporal lobe (MTL), where tau accumulates early. We assessed whether amyloid positivity moderated this relationship.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Vanderbilt Memory & Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: "SuperAgers" are older adults (ages 80+) whose cognitive performance resembles that of adults in their 50s to mid-60s. Factors underlying their exemplary aging are underexplored in large, racially diverse cohorts. Using eight cohorts, we investigated the frequency of APOE genotypes in SuperAgers compared to middle-aged and older adults.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.
Background: Murine studies have identified blood proteins that influence brain aging, but translating these findings to humans remains challenging. We used an innovative approach to investigate whether genetically predicted blood levels of proteins linked to brain aging in animal models are associated with cognitive performance in individuals at risk of Alzheimer's disease (AD) [Figure 1].
Method: Through systematic review, we identified 13 circulating proteins with an aging/rejuvenating effect on the mouse brain.
Alzheimers Dement
December 2024
Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Background: Cerebrovascular pathology frequently co-occurs with Alzheimer's disease (AD) pathology and the combinations of these forms of pathology may underly AD dementia. Sex hormones influence many aspects of cerebrovascular systems and may contribute to cerebrovascular pathology, but many studies of aging and AD do not measure hormones. Therefore, in this study, we explored whether a polygenic score predicting sex hormone levels relates to cerebrovascular pathology in the AD brain.
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