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Efficacy of non -thermal pressure plasma versus other modalities for disinfection of primary root canals.
BMC Oral Health
January 2025
Associate Professor of Operative Dentistry, Conservative Dentistry Department, Faculty of Oral and Dental Medicine Badr University in Cairo, Cairo, Egypt.
Background: Endodontic treatment aims in the preservation of extremely carious primary teeth. For root canal therapy to be successful, root canals must be properly prepared and effectively irrigated .Therefore, it is necessary to select the proper root canal disinfection method to preserve the primary tooth.
View Article and Find Full Text PDFPassion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells.
Sci Rep
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.
Age-related macular degeneration (AMD) is a major cause of vision loss among adults. We investigated the protective effects of passion fruit seed extract (PFSE) and its rich polyphenol piceatannol in an AMD cell model in which human retinal pigment epithelial ARPE-19 cells were exposed to hydrogen peroxide (HO). Using a cell viability WST-8 assay, we revealed that PFSE and piceatannol increased the cellular viability of ARPE-19 cells by 130% and 133%, respectively.
View Article and Find Full Text PDFInhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice.
Nat Commun
January 2025
NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, The province and ministry co-sponsored collaborative innovation center for medical epigenetics, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, 300134, China.
Reactive oxygen species exacerbate nonalcoholic steatohepatitis (NASH) by oxidizing macromolecules; yet how they promote NASH remains poorly understood. Here, we show that peroxidase activity of global hepatic peroxiredoxin (PRDX) is significantly decreased in NASH, and palmitic acid (PA) binds to PRDX1 and inhibits its peroxidase activity. Using three genetic models, we demonstrate that hepatic PRDX1 protects against NASH in male mice.
View Article and Find Full Text PDFEfficacy of different endodontic irrigants in the lesion sterilization and tissue repair technique in primary molars: A randomized controlled clinical trial.
J Indian Soc Pedod Prev Dent
October 2024
Department of Pediatric and Preventive Dentistry, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
Background And Aim: This study aims to evaluate the efficacy of different endodontic irrigants employed in the lesion sterilization and tissue repair (LSTR) technique.
Methods: Forty children aged 4-8 years having at least one primary molar with irreversible pulpitis/pulpal necrosis indicated for pulpectomy were included. Participants were randomly divided into three test groups (Group A, B, and C) and one control group (Group D).
The Phytochemical Composition and Antioxidant Activity of Blossoms and Rhizome Ethanol Extracts.
Nutrients
December 2024
Orthodontics, Department of Conservative Odontology, Faculty of Dental Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Background: Inflammation-induced oxidative stress is a pathophysiological mechanism of inflammatory diseases. Treatments targeting oxidative stress can reduce inflammatory tissue damage.
Objectives: This study aimed to conduct phytochemical analysis and evaluate the antioxidant effects of the hydroalcoholic extract of blossoms () and rhizomes ().
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