Intentional binding refers to a temporal attraction in the perceived times of actions and effects. So far, it has solely been investigated using judgments of the perceived time of actions or their effects. The authors report 3 experiments using an alternative method: the estimation of a time interval between a voluntary action and its subsequent effect. Interval estimates were obtained for intervals bounded by different kinds of actions and effects: The actions were either performed by the participants themselves or by the experimenter. The effects, in turn, were movements either applied to the body of the participant or to the experimenter. First, the results validated interval estimation as a method for exploring action awareness. Second, intentional binding was stronger for self-generated compared with observed actions, indicating that private information about the action contributes to action awareness. In contrast, intentional binding did not depend on whether a somatic effect was applied to the participant's or to another person's body. Third, for self-generated actions, external events gave rise to a stronger intentional binding than did somatic effects. This finding indicates that intentional binding especially links actions with their consequences in the external world.
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http://dx.doi.org/10.1037/0096-1523.33.6.1261 | DOI Listing |
Lancet Diabetes Endocrinol
January 2025
LIB Therapeutics, Cincinnati, OH, USA. Electronic address:
Background: Lerodalcibep, a small binding anti-PCSK9 protein (adnectin), showed effective LDL cholesterol reduction in heterozygous familial hypercholesterolaemia. We aimed to assess the safety and efficacy of lerodalcibep and evolocumab in a globally diverse homozygous familial hypercholesterolaemia population.
Methods: This phase 3, randomised, open-label, crossover, non-inferiority study consisted of two 24-week treatment periods separated by an 8-week washout.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Department of Joint and Bone Surgery, the First Affiliated Hospital of Wannan Medical College, Wuhu Anhui, 241000, P. R. China.
Objective: To explore the feasibility and effectiveness of suture anchor double-pulley technique combined with suture three-dimensional binding via bone tunnel technique for avulsion fractures of the inferior pole of the patella.
Methods: A clinical data of 38 patients with avulsion fractures of the inferior pole of the patella, who met the selective criteria and were admitted between September 2021 and April 2023, was retrospectively analyzed. The fractures were treated with suture anchor double-pulley technique combined with suture three-dimensional binding via bone tunnel technique in 18 cases (group A) and steel wire tension-band fixation in 20 cases (group B).
J Vis
January 2025
Department of Psychology, National Taiwan University, Taipei City, Taiwan.
Intentional binding (IB) refers to the compression of subjective timing between a voluntary action and its outcome. In this study, we investigate the IB of a multimodal (audiovisual) outcome. We used a modified Libet clock while depicting a dynamic physical event (collision).
View Article and Find Full Text PDFClin Lung Cancer
November 2024
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH. Electronic address:
Background: With increased early detection efforts, surgery for early-stage lung cancer is expected to rise. Pafolacianine is the first FDA approved targeted optical imaging agent indicated as an adjunct for intraoperative identification of malignant and nonmalignant pulmonary lesions in adult patients with known or suspected cancer in the lung.
Methods: This is a retrospective review of the malignant and nonmalignant lesions identified by pafolacianine with intraoperative molecular imaging (IMI) in the multi-center Phase 2 and Phase 3 ELUCIDATE clinical trials.
Q J Exp Psychol (Hove)
January 2025
Psychology Department, Université du Québec à Montréal, Montréal, QC, Canada.
There exist indications that sense of agency (SoA), the experience of being the cause of one's own actions and actions' outcomes, is altered in autism. However, no studies in autism have simultaneously investigated the integration mechanisms underpinning both implicit and explicit SoA, the two levels of agency proposed by the innovative cue integration approach. Our study establishes a first complete characterization of SoA functioning in autism, by comparing age- and IQ-matched samples of autistic versus neurotypical adults.
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