Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Exploring Public Interest in Multiple Sclerosis and Its Treatment Measures in the United States: A Google Trends Analysis.
Cureus
November 2024
Department of Dermatology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pimpri-Chinchwad, IND.
Introduction Multiple sclerosis (MS) afflicts over 2.8 million individuals worldwide and is a leading cause of neurological impairment in young adults. This study investigates the public interest in MS and its treatment options in the United States over the past decade, utilizing Google Trends data.
View Article and Find Full Text PDFClinical characteristics and outcomes of autoimmune blistering diseases in Japan.
J Dermatol
October 2024
Department of Dermatology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Article Synopsis
- Autoimmune blistering diseases (AIBDs), such as bullous pemphigoid (BP) and pemphigus vulgaris (PV), cause severe skin and mucosal blistering but are under-researched in Japan due to their rarity and limited medical coverage for less severe cases.
- The study analyzed data from a nationwide database, identifying significant case numbers for different AIBDs, with findings showing that BP patients are generally older and have higher comorbidities compared to other AIBDs.
- In-hospital mortality rates were notably higher for BP and epidermolysis bullosa acquisita (EBA) than for PV and pemphigus foliaceous (PF), with age being a critical risk factor for mortality across
The systemic treatments for drug reaction with eosinophilia and systemic symptoms (DRESS) beyond corticosteroids.
World Allergy Organ J
August 2024
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, China.
Drug reaction with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome (DiHS), is a severe type of cutaneous adverse reaction. The gold standard therapy for DRESS involves the discontinuation of the culprit drug, supportive therapies, and administration of corticosteroids. However, in cases of primary treatment failure or suboptimal response, there arises an urgent need for alternative interventions.
View Article and Find Full Text PDFPemphigoid diseases in patients with end-stage kidney diseases: pathogenesis and treatment.
Front Immunol
July 2024
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Article Synopsis
- - Pemphigoid diseases are autoimmune disorders causing blistering, and their connection with end-stage kidney disease (ESKD) needs more research for effective management.
- - A systematic review found 53 case reports and 8 studies discussing triggers for pemphigoid in ESKD patients, like treatment materials and immune issues, and listed various treatment options.
- - The best management strategy is to eliminate triggers, although corticosteroids are commonly used despite their limited effectiveness, while other treatments like MMF and rituximab show potential benefits that require more research.
Paraneoplastic syndromes in patients with melanoma.
Postepy Dermatol Alergol
June 2024
Department of Dermatology and Vascular Anomalies, John Paul II Centre of Paediatrics, Sosnowiec, Poland.
Article Synopsis
- Paraneoplastic syndromes refer to rare conditions linked to malignant tumors, often caused by tumor-produced substances or autoimmune responses, with melanoma being a notable example associated with diverse systemic manifestations.
- Melanoma can lead to various paraneoplastic syndromes, including neurological and dermatological symptoms, with melanoma-associated retinopathy and neurological conditions like encephalitis being among the most common.
- Treatment mainly involves addressing the underlying melanoma, which may improve symptoms, along with possible immune-modulating therapies like corticosteroids and intravenous immunoglobulins for some cases; further research is needed to better understand these syndromes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!