Background And Objectives: Radiant exposure (RE) is a critical treatment parameter to be optimized for laser hair removal (LHR). An objective and quantitative method to assess the individual maximum safe radiant exposure (IMSRE) would help clinicians optimize LHR while at the same time providing the safest possible laser therapy.
Study Design: Pulsed photo-thermal radiometry (PPTR) measurements were on a total of 403 spots on 13 volunteers. The radiometric signal at 20 milliseconds after the diagnostic laser pulse was used to predict the IMSRE using a simple analytic relationship. Laser pulses (wavelength 755 nm, 3 milliseconds pulse, 50 milliseconds cryogen spray cooling, 30 milliseconds delay) with RE's below and above the predicted IMSRE (range: 10-100 J/cm(2)) were applied and resulting injuries quantified through blind scoring.
Results: IMSRE can be predicted quite robustly with PPTR for the broad range of human skin photo-types (I-IV) considered in this study.
Conclusions: The method presented herein should be useful in helping clinicians optimize LHR on an individual patient basis, with the highest possible safety.
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http://dx.doi.org/10.1002/lsm.20581 | DOI Listing |
Biomed Opt Express
January 2025
Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA.
Deep-UV microscopy enables high-resolution, label-free molecular imaging by leveraging biomolecular absorption properties in the UV spectrum. Recent advances in UV-imaging hardware have renewed interest in this technique for quantitative live cell imaging applications. However, UV-induced photodamage remains a concern for longitudinal dynamic imaging studies.
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December 2024
Federal Office for Radiation Protection, Ingolstaedter Landstrasse 1, 85764, Oberschleissheim, Germany.
Increasing solar ultraviolet radiation (UVR) can raise human exposure to UVR and adversely affect the environment. Precise measurements of ground-level solar UVR and long-term data series are crucial for evaluating time trends in UVR. This study focuses on spectrally resolved data from a UVR measuring station in Dortmund, Germany (51.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
The sensitivity of radiochromic films to UV-blue light is increasingly considered for light dosimetry purposes, owing to their bidimensional detection capabilities and ease of use. While film response to radiation intensity has been widely investigated by commercial scanners, spatial resolution studies remain scarce, especially for small field-of-view applications. These are of growing interest due to the antimicrobial or photo-bio-stimulating effects of UV-blue light sources in in vitro, ex vivo and in vivo models, where precise knowledge of irradiation conditions with adequate spatial resolution is crucial.
View Article and Find Full Text PDFWhile surgical resection is a mainstay of cancer treatment, many tumors are unresectable due to stage, location, or comorbidities. Ablative therapies, which cause local destruction of tumors, are effective alternatives to surgical excision in several settings. Ethanol ablation is one such ablative treatment modality in which ethanol is directly injected into tumor nodules.
View Article and Find Full Text PDFOper Dent
November 2024
Caroline Carrico, PhD, Virginia Commonwealth University School of Dentistry, Richmond, VA, USA.
Objectives: The aim of this study was to measure radiant exposure and time necessary to deliver 16 J/cm2 of radiant exposure to simulated Class I and Class III preparations by first-year dental students. First-year dental students (n=89) received a 60-minute lecture on light-curing. Using the Managing Accurate Resin Curing Patient Simulator (MARC-PS) and protective blue-light-blocking glasses, students twice light-cured Class I and Class III restorations, using the Valo Grand Cordless light-curing unit with infection-control barriers on both Standard and High Power Plus modes.
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